DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17928 and fat-2

DIOPT Version :9

Sequence 1:	NP_001260515.1	Gene:	CG17928 / 35009	FlyBaseID:	FBgn0032603	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_502560.1	Gene:	fat-2 / 178293	WormBaseID:	WBGene00001394	Length:	376	Species:	Caenorhabditis elegans

Alignment Length:	342	Identity:	75/342 - (21%)
Similarity:	123/342 - (35%)	Gaps:	93/342 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 VREKLRKIDYSPTKKTEFLHLGILVSV----FLFSWAGTVLDSLIFKGLAGLALCWVATSTHNYF 187
            |::.|..|.|  ..|...|..|:..:|    ....|.| :|......|:.|.||..|.   |:..
Worm    38 VKDPLTSISY--LIKDYVLLAGLYFAVPYIEHYLGWIG-LLGWYWAMGIVGSALFCVG---HDCG 96

  Fly   188 HQRDSWRMYTFNL--------TMMNFRNWRISHALSHHVYANSLHDLEMSMFEPFLCWIPDSHYA 244
            |...|...:..:|        .:..|..|:.||. .||.|.:   .:|.....|   |:.:..|.
Worm    97 HGSFSDYEWLNDLCGHLAHAPILAPFWPWQKSHR-QHHQYTS---HVEKDKGHP---WVTEEDYN 154

  Fly   245 SKP--QRLISVV-IS------PVVYVV-------------LFQGQFLIRLVLSLTKRNVLCWDDL 287
            ::.  ::..:|: ||      |:..:|             ||:          .|:..|.|  .:
Worm   155 NRTAIEKYFAVIPISGWLRWNPIYTIVGLPDGSHFWPWSRLFE----------TTEDRVKC--AV 207

  Fly   288 IGFSLPIFIYLS---TGVSLLSALLSWEIIISVGSFIFGLVGLTAAHHDPRILHDGDAQRQDF-- 347
            .|.:..|..|::   ...|:.:.:..:.|.:.....|  ||.:|...|          |.:|.
Worm   208 SGVACAICAYIAFVLCDYSVYTFVKYYYIPLLFQGLI--LVIITYLQH----------QNEDIEV 260

  Fly   348 ----DWGLYQVDT-IIDRGDIKWS---DLLVLTHFGEHALHHLFPT-LDHGVLKHLYPELRKTMK 403
                :||..:..| .|||   .|.   |.::......|..||.|.| :.|..|....|.::|.::
Worm   261 YEADEWGFVRGQTQTIDR---HWGFGLDNIMHNITNGHVAHHFFFTKIPHYHLLEATPAIKKALE 322

  Fly   404 EF-DVEL---REINH-W 415
            .. |.:.   ||:|: |
Worm   323 PLKDTQYGYKREVNYNW 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17928	NP_001260515.1	Cyt-b5	33..103	CDD:278597
		Membrane-FADS-like	151..388	CDD:294412	59/284 (21%)
		FA_desaturase	171..412	CDD:278890	60/288 (21%)
fat-2	NP_502560.1	Delta12-FADS-like	39..310	CDD:239584	66/310 (21%)
fat-2	NP_502560.1	FA_desaturase	70..323	CDD:278890	62/290 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900