DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyt-b5-r and SLD1

DIOPT Version :9

Sequence 1:	NP_001260514.1	Gene:	Cyt-b5-r / 35008	FlyBaseID:	FBgn0000406	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_191717.1	Gene:	SLD1 / 825331	AraportID:	AT3G61580	Length:	449	Species:	Arabidopsis thaliana

Alignment Length:	485	Identity:	102/485 - (21%)
Similarity:	164/485 - (33%)	Gaps:	166/485 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ITTHSWQKGKRQDDGAEGLW-RINDGIYDFTSFIDKHPGGPFWIRETKGTDITEAFEAHHLTTA- 86
            ||....:|..:..|    || .|...:|:.:.:|..||||...|....|.|:|:||.|.|..||
plant    10 ITNEDLKKHNKSGD----LWIAIQGKVYNVSDWIKTHPGGDTVILNLVGQDVTDAFIAFHPGTAW 70

  Fly    87 --PEKMIAKYKVRDAAEPRIYTLTLEEGGFYKTLKERVREQLKTIDKRPKKKSDLIHLGLV---- 145
              .:.:...|.:||..       ..|....|:.:....|:                 |||.
plant    71 HHLDHLFTGYHIRDFQ-------VSEVSRDYRRMAAEFRK-----------------LGLFENKG 111

  Fly   146 -VSLYLLGIASAKYNSLLALVLAS------------VALCWT------------VIVSHNYFHRR 185
             |:||.|...:|.:..:|..|||.            :.|.|.            ||:|:..::|.
plant   112 HVTLYTLAFVAAMFLGVLYGVLACTSVFAHQIAAALLGLLWIQSAYIGHDSGHYVIMSNKSYNRF 176

  Fly   186 DNWQMYAFN-LGMMNFAAWRVSHALSHHIYPNS--------------------------YFDLEL 223
            .  |:.:.| |..::.|.|:.:|. :||:..||                          ::|.:|
plant   177 A--QLLSGNCLTGISIAWWKWTHN-AHHLACNSLDYDPDLQHIPVFAVSTKFFSSLTSRFYDRKL 238

  Fly   224 SMFEPLLCWVPNPHIKSKLMRYVSWVTEPVAY--ALAFFIQMGTRIF-------YSLRHTNILYW 279
            : |:|         :...|:.|..:...||..  .:..|||....:|       .:|....||.:
plant   239 T-FDP---------VARFLVSYQHFTYYPVMCFGRINLFIQTFLLLFSKREVPDRALNFAGILVF 293

  Fly   280 HDLLPLTIPIAIYLGTGGSLGIWICVRQW----------LAMTSIASFSFCLIGLNAAHHDPEIY 334
            ....||.:.               |:..|          ..:|::....|.|     .|...::|
plant   294 WTWFPLLVS---------------CLPNWPERFFFVFTSFTVTALQHIQFTL-----NHFAADVY 338

  Fly   335 HEGDANREDRDWGLFQVDTIID---RGDLKWSQFLVLTHFGD---HVLHHLFPTLDHGLLPALYP 393
            ......   .||...|....||   |..:.|       .||.   .:.|||||.|....|..:.|
plant   339 VGPPTG---SDWFEKQAAGTIDISCRSYMDW-------FFGGLQFQLEHHLFPRLPRCHLRKVSP 393

  Fly   394 VL----------YQTLDEFKGHLRECNHIE 413
            |:          |:::..|:.::...|.::
plant   394 VVQELCKKHNLPYRSMSWFEANVLTINTLK 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyt-b5-r	NP_001260514.1	Cyt-b5	26..98	CDD:278597	22/75 (29%)
		FA_desaturase	161..408	CDD:278890	64/332 (19%)
		Membrane-FADS-like	<328..385	CDD:294412	17/62 (27%)
SLD1	NP_191717.1	Cyt-b5	11..82	CDD:395121	23/74 (31%)
SLD1	NP_191717.1	Delta6-FADS-like	143..404	CDD:239583	58/303 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	45	1.000	Inparanoid score	I2674
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1060606at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.870