DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mhc and AT5G13560

DIOPT Version :9

Sequence 1:	NP_001162991.1	Gene:	Mhc / 35007	FlyBaseID:	FBgn0264695	Length:	1962	Species:	Drosophila melanogaster
Sequence 2:	NP_196860.2	Gene:	AT5G13560 / 831200	AraportID:	AT5G13560	Length:	679	Species:	Arabidopsis thaliana

Alignment Length:	743	Identity:	147/743 - (19%)
Similarity:	279/743 - (37%)	Gaps:	203/743 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1325 RATLLGKFRNLEHDLDNLREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAK 1389
            :|..:|..:|:...:.|..:.|.:.| |:|                              :.|..
plant    10 KAVEVGNRKNITRTVKNYADSVVQHA-GQA------------------------------VAEGA 43

  Fly  1390 RKLQARLA-----EAEETIESLNQKCIGLE-KTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAF 1448
            :..|.|:.     ...:||:.|.:..:... :.:..|.|....:..|:|||.  .::.:.||.:.
plant    44 KLFQDRIGVGAYKSVHQTIQRLEEAAVSYRGQERALLITRWLSVLKEIDRAT--DSSLKDKQLSS 106

  Fly  1449 DKIIG-------EWKLKVD-DLAAE-LDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNL 1504
            ::.:.       ||.|..| |:..| |:......::.:.|...|....|...:
plant   107 EEQLASDEAKKREWVLYYDPDIGGEPLNFRDVFLQSQALEGIVLSMIIEPPHD------------ 159

  Fly  1505 ADEVKDLLDQIG---EGGRNIHE-----IEKARKRLEAEKDELQAALEEAEAALEQEEN------ 1555
             :|:..||:..|   .||:.:|:     ::.......:.|||:   |.:.:..|:..:|
plant   160 -EEITLLLEMFGLCLNGGKEVHDAIVSSMQDLATVFSSYKDEV---LVKQDELLQFAQNAITGLK 220

  Fly  1556 ---KVLRAQLELSQVRQEIDR----RIQEKEEEFENTRKNHQRALDSMQASLEAEAK----GKAE 1609
               ::||...|.|.:|:::::    :|.::.|:     |.|:....:::|..|..||    .:.|
plant   221 INAEMLRIDAEASDLRKKLEKMNASQIPQESED-----KEHKETPLTIEAFKETLAKIRLCSRLE 280

  Fly  1610 ALRMKKKLEAD----------INELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARD 1664
            .|.::|:..::          :::|.:.|:....:.::|:|.|...:.|       .||..:||.
plant   281 GLLIRKRQLSNGDSPDIHAQKVDKLRVLLESLANSTSKAEKRISENRLQ-------KEEALKARV 338

  Fly  1665 DAREQLGISERRANALQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKL 1729
            ....:.|..|:...|...:||:.|..|| ||  .::....||.|..:....:.:......|..::
plant   339 VKANETGEKEKELGAEIAQLEKQRDELE-AD--LKRVNLSLAAAQARFRNATEERDQFGEANNQI 400

  Fly  1730 ESELQTLHSDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQV 1794
            .:.|:|...||.:.:...| .|.:..|..::.  |.|....:..|.:|::|      |.:.||:.
plant   401 IAHLKTKDDDLSKSVVACK-KEAEVIKTWINF--LEDTWLLQCSHIETKDK------QTLDELEK 456

  Fly  1795 RLD---EAEANALKGGKK----AIQKLEQRVRELENELDG-EQRRHADAQKNLRKSERRVKELSF 1851
            ..|   :...|.|...||    .|.::|..|..|:|...| |:..:||...|...:.|::.|..:
plant   457 HEDYFSDVALNILSVYKKEVAPLISRIENYVENLKNLGPGSEKPPNADQGDNQVSNPRKILEEEY 521

  Fly  1852 ------------------------QSEEDRKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNL 1892
                                    ||:.|:|:..|:::|.|.::       :..::.|.||...|
plant   522 IDYETKIITTFSIVDNVKEQFQVLQSKLDKKDDRRVKELFDDME-------KMRQQFESIARPTL 579

  Fly  1893 AKFRKAQQELEEAEERADLAEQAISKFRAKGRAGSVGRGASPAPRATSVR--------------- 1942
                    |:|....|:.:.....|....|          ||.|.::|:.
plant   580 --------EIEIPSPRSSVTSPKSSATSPK----------SPKPSSSSMNASTESTQTQKPELSN 626

  Fly  1943 -PQFDGLA------FPPRFDLAP-ENEF 1962
             ||....|      |.|..:||. |:||
plant   627 SPQAPNPAAGSSQEFNPEAELAELESEF 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mhc	NP_001162991.1	Myosin_N	36..73	CDD:280832
		MYSc	81..777	CDD:214580
		MYSc_Myh1_insects_crustaceans	100..765	CDD:276874
		Myosin_tail_1	842..1897	CDD:279860	128/653 (20%)
		V_Alix_like	1557..1877	CDD:187408	79/369 (21%)
		ATP-synt_B	<1671..1771	CDD:304375	23/99 (23%)
		TMPIT	1739..>1825	CDD:285135	23/92 (25%)
AT5G13560	NP_196860.2	Fib_alpha	469..>551	CDD:285864	17/81 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000