Protein Alignment Mhc and ninaC

DIOPT Version :10

• Sequence 1: NP_523587.4
• Gene: Mhc / 35007
• FlyBaseID: FBgn0264695
• Length: 1962
• Species: Drosophila melanogaster
• Sequence 2: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Alignment Length: 1013
• Identity: 242/1013 - (23%)
• Similarity: 442/1013 - (43%)
• Gaps: 174/1013 - (17%)

  Fly    83 PKYEKAEDMSNLTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKR 147
            |:....||::.|....|.:::.:||.|......|::.|...:::|..:....:.......||.|.
  Fly   329 PEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKS 393

  Fly   148 RNEVPPHIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGASKKTDEAAKSK 212
            |:|..||||:::|.||.|||.:...|.::::|||.:||:.|.:.:|.:...:|     |....:.
  Fly   394 RSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLG-----DGNRGAT 453

  Fly   213 GSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAGADIETYLLEKARVISQQS 277
            |.:|..:    ..:....||.|..|::|:|......:.||.|||::||....|:|||.||.:...
  Fly   454 GRVESSI----KAILMLVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDG 514

  Fly   278 LERSYHIFYQIMS--GSVPGVKDICLLTDNIYDYHIVSQGKVTVASI----DDAE-------EFS 329
            .:.::||||....  .....:|:..|..|..|.|..|.. :|..:.:    ||.|       ||.
  Fly   515 TQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYLRVPP-EVPPSKLKYRRDDPEGNVERYREFE 578

  Fly   330 --LTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEEGGRVSKLFGCDTA 392
              |.|     :.|..::.|.|.::.||::::|.::|:|.|:  .||.:..:...|:::|...|..
  Fly   579 NILRD-----IDFNHKQLETVRKVLAAILNIGNIRFRQNGK--YAEVENTDIVSRIAELLRVDEK 636

  Fly   393 ELYKNL-----LKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLVKKCNETL------ 446
            :...:|     :|..|....::.|     ::..::..|:...::.||..:::.:.|..:
  Fly   637 KFMWSLTNFIMVKGGIAERRQYTT-----EEARDARDAVASTLYSRLVDFIINRINMNMSFPRAV 696

  Fly   447 --DTQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQEEYQREGIEWTF 509
              ||     :.|.:.|:.|||.|..||.|||.||..||::|..:|..:|:.|..|.:.|.|:...
  Fly   697 FGDT-----NAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTIN 756

  Fly   510 IDFGMDLQLCID-LIEKPMGILSILEEESMFPKATDQ-TFSEKLTNTHLGKSAPFQKPKPPKPGQ 572
            ::| .|.:..:| |:.||.|:..|:::.|.  ...|| ...::::..|    :.|.|.      .
  Fly   757 LNF-YDNKTALDNLLTKPDGLFYIIDDASR--SCQDQDLIMDRVSEKH----SQFVKK------H 808

  Fly   573 QAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLIEIFADHAGQSGG------G 631
            .|...::|||.|.:.|:...:.:.|:|.:...:::.|:.|.::.::.:|.:...::|.      .
  Fly   809 TATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEA 873

  Fly   632 EQAKGGRGKKGGGFATVSSAYKEQLNSL-----------MTTLRSTQP------HFVRCIIPNEM 679
            .|.|....:|.....|:|:....|:|:|           :|.|:....      ||||||..:..
  Fly   874 VQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLE 938

  Fly   680 KQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLLQGVEKDKKATEII 744
            .:|....:.:|..|:...|||:.:...:|||.:|:.:.:|..||:.:.....:.||..|....::
  Fly   939 YKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKDNCRLL 1003

  Fly   745 IKFIDLPEDQYRLGNTKVFFR---AGVLGQMEEFRDERLGKIMSWMQA-WAR-----GYLSRKGF 800
              |:.|..:.:.||.||||.|   ...|.::.|.:.:::.|:.|.|:| .||     |.:.:.|.
  Fly  1004 --FLRLKMEGWALGKTKVFLRYYNDEFLARLYELQVKKVIKVQSMMRALLARKRVKGGKVFKLGK 1066

  Fly   801 KKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEIARLEEK--------AKK 857
            |..:...||...:|:..|.:......|         ||:|     ::..:|.|.        |||
  Fly  1067 KGPEHHDVAASKIQKAFRGFRDRVRLP---------PLVN-----EKSGQLNENTADFIRPFAKK 1117

  Fly   858 AEE-------LH--AAE----VKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTA 909
            ..|       ||  ||.    |.:.:::...|.:::|.......::..|:..:::..      ::
  Fly  1118 WREKSIFQVLLHYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERINMREVN------SS 1176

  Fly   910 QKNDLENQLRDIQERLTQ-----------------EEDARNQLFQQKKKADQE-ISGLKKDIE-- 954
            |...|...::.:..||.|                 .:...|||..|..:.|:. .|.|:::..
  Fly  1177 QLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDEPWDSPLQRNPSMT 1241

  Fly   955 --DLELNVQKAEQDKATKDHQIRNLNDEIAHQDELINK 990
              .|..|..|.||...|.       .|.:...|.:.|:
  Fly  1242 SCALTYNAYKKEQACQTN-------WDRMGESDNIYNQ 1272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mhc	NP_523587.4	Myosin_N	33..75	CDD:460670
		MYSc_Myh1_insects_crustaceans	100..765	CDD:276874	182/717 (25%)
		Myosin_tail_1	842..1922	CDD:460256	35/192 (18%)
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	182/717 (25%)