Protein Alignment Mhc and LOC100495802

DIOPT Version :9

• Sequence 1: NP_001162991.1
• Gene: Mhc / 35007
• FlyBaseID: FBgn0264695
• Length: 1962
• Species: Drosophila melanogaster
• Sequence 2: XP_031747898.1
• Gene: LOC100495802 / 100495802
• -ID: -
• Length: 1937
• Species: Xenopus tropicalis
• Alignment Length: 1924
• Identity: 1072/1924 - (55%)
• Similarity: 1429/1924 - (74%)
• Gaps: 19/1924 - (0%)

  Fly    16 YLFVSLEQRRIDQSKPYDSKKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGEVRDIKSEKVEKV 80
            ||..|.::|...||||:|:|.:.::.|.||.|:.|.:.|.:...|:|....|....:|..::...
 Frog    15 YLRKSEKERIEAQSKPFDAKNTVFVDDAKELYVKGMVTAREDGKVTVKTDAGNNVTVKDSQIYPQ 79

  Fly    81 NPPKFEKIEDMADMTVLNTPCVLHNLRQRYYAKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRG 145
            ||||::||||||.||.||...||:||::||.|.:||||||||||.:||||..|||.......|||
 Frog    80 NPPKYDKIEDMAMMTHLNEASVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAGYRG 144

  Fly   146 KRRNEVPPHIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGA----SKKTD 206
            |:|.|.|||||:|||.||..|||:..|||:|||||||||||.|||:||.||||:.|    .||.:
 Frog   145 KKRVEAPPHIFSISDNAYQAMLTDRENQSVLITGESGAGKTVNTKRVIQYFATIAAIGDSGKKKE 209

  Fly   207 EAAKSKGSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAGADIETYLLEKAR 271
            .:...:|:||||::|.||:|||||||||||||||||||||||||||.||||:.||||||||||:|
 Frog   210 PSNSLQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLSSADIETYLLEKSR 274

  Fly   272 VISQQSLERSYHIFYQIMSGSVPGVKDICLLTDNIYDYHIVSQGKVTVASIDDAEEFSLTDQAFD 336
            |..|.|.|||||||||:|:...|.:.::||:|.|.||:..:|||::.|.||||.||...||.|.|
 Frog   275 VTFQLSAERSYHIFYQMMTNKKPEIIEMCLITTNPYDFPFISQGEIVVKSIDDQEELMATDSAID 339

  Fly   337 ILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEEGGRVSKLFGCDTAELYKNLLKP 401
            ||||.:.||..:|::|.||||...|||||:.||||||.||.|:..:::.|.|.::|:|.|.|..|
 Frog   340 ILGFNQDEKVGIYKLTGAVMHHSNMKFKQKQREEQAEPDGTEDADKIAYLMGLNSADLLKALCYP 404

  Fly   402 RIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLVKKCNETLDTQQKRQHFIGVLDIAGFEI 466
            |:||||||||:|:.|.||.|::|||||.|:::||.|:|.:.|:.|||:|.||.||||||||||||
 Frog   405 RVKVGNEFVTKGQTVGQVNNAVGALCKSVYEKLFLWMVTRINQQLDTKQPRQFFIGVLDIAGFEI 469

  Fly   467 FEYNGFEQLCINFTNEKLQQFFNHHMFVLEQEEYKREGIDWAFIDFGMDLLACIDLIEKPMGILS 531
            |::|..|||||||||||||||||||||||||||||:|||||.||||||||.|||:||||||||.|
 Frog   470 FDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIDWEFIDFGMDLAACIELIEKPMGIFS 534

  Fly   532 ILEEESMFPKATDQTFSEKLTNTHLGKSAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEK 596
            |||||.|||||||.:|..||...||||...|:||||.| |:..|||::.||||.|.|||:|||:|
 Frog   535 ILEEECMFPKATDTSFKNKLYEQHLGKCKNFEKPKPGK-GKAEAHFSLGHYAGTVDYNISGWLDK 598

  Fly   597 NKDPLNDTVVDQFKKSQNKLLIEIFADHA---GQSGGGEQAKGGRGKKGGGFATVSSAYKEQLNS 658
            ||||||::||..::||..|||..:::.:|   ..:||    |||:.|||..|.|||:.::|.||.
 Frog   599 NKDPLNESVVQLYQKSSVKLLSFLYSSYAAADADAGG----KGGKKKKGSSFQTVSALFRENLNK 659

  Fly   659 LMTTLRSTQPHFVRCIIPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRY 723
            |||.||||.||||||:||||.|.||:::.||::|||.||||||||||||||||:|::|.|||.||
 Frog   660 LMTNLRSTHPHFVRCLIPNESKTPGIMENHLIIHQLRCNGVLEGIRICRKGFPSRILYGDFKQRY 724

  Fly   724 KIMCPKLL---QGVEKDKKATEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMS 785
            |::....:   |.:: .|||:|.::..||:...||:.|:|||||:||:||.:||.|||:|.::::
 Frog   725 KVLNASAIPDGQFID-SKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLIT 788

  Fly   786 WMQAWARGYLSRKGFKKLQEQRVALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEIAR 850
            ..||..||:|.|..||::.|:|.::..:|.|||.::.::.|||.||:.|:||||..:..|.|:..
 Frog   789 RTQALCRGFLMRVEFKQMMERRESIYTIQYNLRSFMNVKHWPWMKLYFKIKPLLKSAETEKEMQN 853

  Fly   851 LEEKAKKAEE-LHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKNDL 914
            ::|:.:|.:: |..||.| :||||.....||.||..|...:..|...|.|.:||...|...|..|
 Frog   854 MKEEFEKTKDALAKAEAK-KKELEEKMVVLLQEKNDLSLQVQTESETLADSEERCEGLIKVKIQL 917

  Fly   915 ENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDHQIRNLND 979
            |:::::|.|||..||::..:|..:|:|.:.|.|.|||||:||||.:.|.|::|...:::::||.:
 Frog   918 ESKIKEITERLEDEEESNAELTAKKRKLEDETSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 982

  Fly   980 EIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVR 1044
            |:|..||.|:||.||||...|.:|:|.::|||.|||::.|.|.|.||||.:|:||.|||:|||:|
 Frog   983 EMAVLDENISKLTKEKKALQEAHQQTLDDLQAEEDKVSSLTKAKTKLEQQVDDLEGSLEQEKKLR 1047

  Fly  1045 GDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKE 1109
            .|:|::|||:||||||:||.|.|||.:|::.|:.:::||.|:|.:..|:||||.:..:.|::|||
 Frog  1048 LDLERAKRKLEGDLKLSQETVMDLENDKQQTEEKLKKKDFEISQLQGKIEDEQTLGTQLQKKIKE 1112

  Fly  1110 LQARIEELEEEVEAERQARAKAEKQRADLARELEELGERLEEAGGATSAQIELNKKREAELSKLR 1174
            |||||||||||:||||.||||.|||||||:|||||:.|||||||||||||||:|||||||..|:|
 Frog  1113 LQARIEELEEEIEAERAARAKIEKQRADLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKVR 1177

  Fly  1175 RDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKNEYYGQLNDLRAGVDHITN 1239
            ||||||.:|||:|...|||||.|:|||:.||:|.|.::|.|.||||:|...:::||.:.:::::.
 Frog  1178 RDLEEATLQHEATAGALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNLENVSK 1242

  Fly  1240 EKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEEAESQVSQLSKIK 1304
            .||..||:.:.::..|:||:||.||..|.:||..|.:.:...||.:|.||:||.||.:||||:.|
 Frog  1243 AKANLEKVNRVIEDQLSEVKSKGDEQQRLVNDLGAQRARFQTENGELSRQVEEKESLISQLSRGK 1307

  Fly  1305 ISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDNLREQVEEEAEGKADLQRQLSKANAEAQV 1369
            ...|.|:|:.||..:|||:.:..|....::..||.|.||||.|||.|.||:|||.|||||.|...
 Frog  1308 QGFTQQIEELKRQLEEESKAKNALAHALQSARHDSDLLREQYEEEQEAKAELQRSLSKANGEVAQ 1372

  Fly  1370 WRSKYESDGVARSEELEEAKRKLQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRA 1434
            ||:|||:|.:.|:|||||||:||..||.||||.:|::|.||..|:||||||.:|||||.::|:||
 Frog  1373 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEQVEAVNSKCASLDKTKQRLQSEVEDLMVDVERA 1437

  Fly  1435 NAIANAAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRR 1499
            |:.|.|.:|||:.|||::.|||.|.::..|||:|:.||.|:.|||:|::|.||||..|.:|.::|
 Frog  1438 NSAAAALDKKQRNFDKVLSEWKQKYEEGQAELEAALKEARSQSTEIFKVKNAYEESLEHVETLKR 1502

  Fly  1500 ENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLEL 1564
            |||||..|:.||.:||||.|::|:|:|||:|::|.||.:|||||||||.:||.||.|:||.||||
 Frog  1503 ENKNLQQEISDLTEQIGETGKSINELEKAKKQVEQEKSDLQAALEEAEGSLEHEEAKILRIQLEL 1567

  Fly  1565 SQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALD 1629
            :||:.|:||:|.||:||.|..::|.|||:|::|::|::|.:.:.:|||:|||:|.|:|||||.|.
 Frog  1568 NQVKSEVDRKIAEKDEENEQLKRNSQRAIDTIQSTLDSEIRSRNDALRLKKKMEGDLNELEIQLS 1632

  Fly  1630 HANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQA 1694
            |||:...||||.::..|.|.||.|..|::..|.:||.:||:.:.|||.|..|.|:||:|..|||.
 Frog  1633 HANRQAGEAQKQLRNVQAQYKDAQLQLDDAVRGQDDLKEQVAVIERRNNLQQAEIEENRAALEQT 1697

  Fly  1695 DRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMV 1759
            :|.|:.|||||.||.|::..:.:||.|:..:|:|||::|..|.::::|.:.||:|:|||||||:.
 Frog  1698 ERSRKIAEQELLDASERVQLLHSQNTSLIGSKKKLEADLSQLQNEVEEAVQEARNAEEKAKKAIT 1762

  Fly  1760 DAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEANALKGGKKAIQKLEQRVRELENE 1824
            |||.:|:||:.|||.:...|:::|.|||.:|:||.||||||..|:|||||.:||||.||||||||
 Frog  1763 DAALMAEELKKEQDTSAHLERMKKNLEQTVKDLQNRLDEAEQLAMKGGKKQLQKLESRVRELENE 1827

  Fly  1825 LDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAA 1889
            ||.||:|..||.|.:||.|||||||::|:||||||..|:||||||||.|:|.||||.||:||.|.
 Frog  1828 LDNEQKRGVDAVKGVRKYERRVKELTYQTEEDRKNVLRLQDLVDKLQLKVKAYKRQAEESEEQAT 1892

  Fly  1890 LNLAKFRKAQQELEEAEERADLAEQAISKFRAKGR-AGS 1927
            .:|::|||.|.||||||||||:||..::|.|||.| |||
 Frog  1893 THLSRFRKVQHELEEAEERADIAESQVNKLRAKSRDAGS 1931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mhc	NP_001162991.1	Myosin_N	36..73	CDD:280832	9/36 (25%)
		MYSc	81..777	CDD:214580	439/705 (62%)
		MYSc_Myh1_insects_crustaceans	100..765	CDD:276874	418/674 (62%)
		Myosin_tail_1	842..1897	CDD:279860	562/1055 (53%)
		V_Alix_like	1557..1877	CDD:187408	175/319 (55%)
		ATP-synt_B	<1671..1771	CDD:304375	48/99 (48%)
		TMPIT	1739..>1825	CDD:285135	51/85 (60%)
LOC100495802	XP_031747898.1	Myosin_N	34..72	CDD:397036	10/37 (27%)
		MYSc_class_II	99..768	CDD:276951	418/674 (62%)
		Myosin_tail_1	848..1925	CDD:396244	579/1077 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D41153at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010