DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk17 and Asic1

DIOPT Version :9

Sequence 1:	NP_001285988.1	Gene:	ppk17 / 35006	FlyBaseID:	FBgn0032602	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_006257440.1	Gene:	Asic1 / 79123	RGDID:	71062	Length:	559	Species:	Rattus norvegicus

Alignment Length:	463	Identity:	89/463 - (19%)
Similarity:	164/463 - (35%)	Gaps:	103/463 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LFACCIVVIVQLYECFA------KLYNPPISTHSYYSLNETIEMPSVTICREPPYKEEVLTRLS- 81
            |:|...|:.:..:.|..      .|..|.::.....:..|.: .|:||.|.....:   |::||
  Rat    90 LWAVAFVIALGAFLCQVGDRVAYYLSYPHVTLLDEVATTELV-FPAVTFCNTNAVR---LSQLSY 150

  Fly    82 -----------------GGACPHPKYATCWMKYPFGEISLDEFFENSTHDSGDTFVFYG-----L 124
                             .|....|.....:...||   :|..|:..|.|...|..::..     .
  Rat   151 PDLLYLAPMLGLDESDDPGVPLAPPGPEAFSGEPF---NLHRFYNRSCHRLEDMLLYCSYCGGPC 212

  Fly   125 NEDKNNVVMNSSLHFYMGRCYTL------RPKESAKRVSKAVGYSIML----EHSMLTTSVSDVD 179
            .....:||...     .|:|||.      ||:....:.....|..|||    :..:.....:|..
  Rat   213 GPHNFSVVFTR-----YGKCYTFNSGQDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDET 272

  Fly   180 TGSVGWHVFIHDKKENFTEINMKGSGRVE--YVFVGVNEEIEIKLQTQYFS-NVQTREEACSDDE 241
            :...|..|.||.:.|. ..|:..|.|...  ..||...|:..|.|.:.:.: |..|.:....|
  Rat   273 SFEAGIKVQIHSQDEP-PFIDQLGFGVAPGFQTFVSCQEQRLIYLPSPWGTCNAVTMDSDFFD-- 334

  Fly   242 NYSDLKCGEQCIWQDLADNMQC-----------SGPWMHEIASEPCNDSLSMRKLISDYKDVYEN 295
            :||...|...|..:.|.:|..|           ..|..::..::|..|.|            .|.
  Rat   335 SYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKECADPALDFL------------VEK 387

  Fly   296 EDDFDCDCVQPCQ--------------SRIYTTFIQNRKAFNQPEPR-----TQIYIYYTTKLIS 341
            :.:: |.|..||.              |:....::  .|.||:.|..     ..:.|::......
  Rat   388 DQEY-CVCEMPCNLTRYGKELSMVKIPSKASAKYL--AKKFNKSEQYIGENILVLDIFFEVLNYE 449

  Fly   342 MIEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHMMLFFCGGFIKRMQQKEQAKLEANSED 406
            .||::.:|:....:.|:||.:|..:|.|:|.::.:.::..........:|.:.:::|| .::::.
  Rat   450 TIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHRLCRRGKCQKEAK-RSSADK 513

  Fly   407 GQSQTSDE 414
            |.:.:.|:
  Rat   514 GVALSLDD 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	77/405 (19%)
Asic1	XP_006257440.1	ASC	63..541	CDD:295594	89/463 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345635
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840