Protein Alignment ppk17 and SCNN1G

DIOPT Version :9

• Sequence 1: NP_001285988.1
• Gene: ppk17 / 35006
• FlyBaseID: FBgn0032602
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001030.2
• Gene: SCNN1G / 6340
• HGNCID: 10602
• Length: 649
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 104/559 - (18%)
• Similarity: 162/559 - (28%)
• Gaps: 241/559 - (43%)

  Fly    22 LVLFACCIVVIVQLYECFAKLYNPPISTHSYYSLNETIEMPSVTICREPPYK------------- 73
            |:|:.|.::|.        ..|...:|...::   ..::.|:||||...|||
Human    66 LILWQCALLVF--------SFYTVSVSIKVHF---RKLDFPAVTICNINPYKYSTVRHLLADLEQ 119

  Fly    74 --EEVLTRLSGGACPHP---KYATCWMKYPFGE------------ISLDE------FF------- 108
              .|.|..|.|  .|..   :.|..|.....|:            ...||      ||
Human   120 ETREALKSLYG--FPESRKRREAESWNSVSEGKQPRFSHRIPLLIFDQDEKGKARDFFTGRKRKV 182

  Fly   109 --------ENSTH--------------DSGD--TFVF-YGLN-------------------EDKN 129
                    .|..|              |:.|  |:.| .|:|                   |.|.
Human   183 GGSIIHKASNVMHIESKQVVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKI 247

  Fly   130 NV-------------------VMNSSL--HFYMGRCYTLRPKESAKRVSKAVGYSIMLEHSMLTT 173
            |:                   ..|.:|  |...|.|||...:|:...:|.::|.|
Human   248 NMSYSAEELLVTCFFDGVSCDARNFTLFHHPMHGNCYTFNNRENETILSTSMGGS---------- 302

  Fly   174 SVSDVDTGSVGWHVFIHDKKENFTEINMKGSG-------RVEYVFV-GVNEEIE----------- 219
                    ..|..|.::..:|.:....:..:|       :.||.|| .|..|||
Human   303 --------EYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHL 359

  Fly   220 ---IKLQTQYFSNVQTREEACSDDEN-----------YSDLKCGEQCIWQDLADNMQC---SGP- 266
               .||...|        ..|::|.:           ||...|...|....:.:...|   |.|
Human   360 TESFKLSEPY--------SQCTEDGSDVPIRNIYNAAYSLQICLHSCFQTKMVEKCGCAQYSQPL 416

  Fly   267 --------------WMHEIASEPCNDSLSMRKLISDYKDVYENEDDFDCD--CVQPCQSRIYT-- 313
                          ||:      |...|. |..:         :::..|.  |.:.|..:.:|
Human   417 PPAANYCNYQQHPNWMY------CYYQLH-RAFV---------QEELGCQSVCKEACSFKEWTLT 465

  Fly   314 -------------------TFIQNR---KAFNQPEPRTQIYIYYTTKLISMIEERPSYDTTQFIA 356
                               |:.|.|   |..|:.: ..::.|:|.......|.|.|:......::
Human   466 TSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTD-LAKLLIFYKDLNQRSIMESPANSIEMLLS 529

  Fly   357 DVGGSLGFLLGLSVLGLIGILEHMMLFFCGGFIKRMQQK 395
            :.||.||..:..||:.:|.|:|...:.|.....:|..||
Human   530 NFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQK 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	91/520 (18%)
SCNN1G	NP_001030.2	ENaC	24..630	CDD:273304	104/559 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152190
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.830