Protein Alignment ppk17 and ASIC4

DIOPT Version :9

• Sequence 1: NP_001285988.1
• Gene: ppk17 / 35006
• FlyBaseID: FBgn0032602
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_061144.4
• Gene: ASIC4 / 55515
• HGNCID: 21263
• Length: 539
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 80/377 - (21%)
• Similarity: 143/377 - (37%)
• Gaps: 82/377 - (21%)

  Fly    62 PSVTICREPPYKEEVLT--------RLSGGACPHPK----YATCWMKYPFGEISLDEFFENSTHD 114
            |:||:|....::...|:        .|:|  .| ||    :....::||  |..:.:....:.|.
Human   113 PAVTLCNINRFRHSALSDADIFHLANLTG--LP-PKDRDGHRAAGLRYP--EPDMVDILNRTGHQ 172

  Fly   115 SGDTFV---FYGLNEDKNNVVMNSSLHFYMGRCYTLRPKESAKRVSKA----VGYSIML----EH 168
            ..|...   |.|.:...:|.   |.::...|:|||......:...|:|    .|..|||    |.
Human   173 LADMLKSCNFSGHHCSASNF---SVVYTRYGKCYTFNADPRSSLPSRAGGMGSGLEIMLDIQQEE 234

  Fly   169 SMLTTSVSDVDTGSVGWHVFIHDKKENFTEINMKGSGRVE--YVFVGVNEEIEIKLQTQYFSNVQ 231
            .:.....::..:...|..|.||.::|. ..|:..|.|...  ..||...|: .:....|.:.|.:
Human   235 YLPIWRETNETSFEAGIRVQIHSQEEP-PYIHQLGFGVSPGFQTFVSCQEQ-RLTYLPQPWGNCR 297

  Fly   232 TREEACSDD-ENYS-------DLKCGEQCIWQDLADNMQCSGPWMHEIASEPCNDSLSMRKL--- 285
            ...|....: :.||       .|:|.::.:.|      :|....:|    .|.|:::....:
Human   298 AESELREPELQGYSAYSVSACRLRCEKEAVLQ------RCHCRMVH----MPGNETICPPNIYIE 352

  Fly   286 ISDYK-DVYENEDDFDCDCVQPCQ-----SRIYTTFIQNR-------KAFNQPEPRTQIYI---- 333
            .:|:. |......:..|.|..||.     ..|....|.||       :.:|    |.:.||
Human   353 CADHTLDSLGGGPEGPCFCPTPCNLTRYGKEISMVRIPNRGSARYLARKYN----RNETYIRENF 413

  Fly   334 -----YYTTKLISMIEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHM 380
                 ::.......:|:|.:|..:..:.|:||.:|..:|.|:|.|:.||:::
Human   414 LVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYI 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	70/353 (20%)
ASIC4	NP_061144.4	ASC	40..488	CDD:413546	80/377 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152196
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740