DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk17 and ppk19

DIOPT Version :9

Sequence 1:	NP_001285988.1	Gene:	ppk17 / 35006	FlyBaseID:	FBgn0032602	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	94/459 - (20%)
Similarity:	161/459 - (35%)	Gaps:	122/459 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LYNPPISTHS---YYSLNET-------IEMPSVTIC--------REP----------PYKE---- 74
            ||...:..||   ..||.||       |:.|:|.:|        |.|          |..|
  Fly    74 LYTVLMHRHSEQLLVSLIETTQLPVYHIDFPAVAVCPWNHFNWQRAPSAFIRFLPRHPNAELRET 138

  Fly    75 -------------------EVLTRLSGGACPHPKYATC--WMKYPFGEISLDE--FFENSTHD-- 114
                               .:||:.:.....:.|....  :|.|...|:.:.:  .|:.:.:|
  Fly   139 FRQLLASMDIMNFSNFNRIRILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDETPYDCC 203

  Fly   115 ---------SGDTFVFYGL---NEDKNNVVMNSSLHFYMGRCYTLRPKESAKRVSKAVGYSIMLE 167
                     .|...||..:   |..|.:::.    .||..:..| ..::|..:.:....||.|..
  Fly   204 KLFVREQTVKGQCLVFNSMISENSRKKHLIN----QFYPHKLST-AGEDSGLKFTINASYSFMNN 263

  Fly   168 HSMLTTSVSDVDTGSVGWHVFIHDKKENFTEINMKGSGRVEYVFVGVNEEIEIKLQTQYFSNVQT 232
            ...||         ..|.::.|.:.::...|:........|. ||.|:..:.......|..:.:.
  Fly   264 IDALT---------PFGMNLMIKEPRQWSNEMMYHLYPDTEN-FVAVHPLVTETSPNTYEMSPKK 318

  Fly   233 REEACSDDEN---------YSDLKCGEQCIWQDLADNMQCSGP-WMHEIASEP--------C--- 276
            |.....|::|         |:...|...|:...:....|||.| ::..|...|        |
  Fly   319 RRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGN 383

  Fly   277 -NDSLSMRKLISDYKDVYENEDDFDCDCVQPCQSRIYTTFIQNRKAFNQPEPRT----QIYIYYT 336
             :|..:..|:....|.:.::.....|||...|.||:|...:..|| .:.|:..|    :..:||.
  Fly   384 NSDIFTYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRK-LDYPKNSTDQLIKAQVYYG 447

  Fly   337 TKLISMIEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHMMLFFCG----GFIK--RMQQK 395
            .::::.|..:..|.....:|:.||.:...:|.||:..|     .:||..|    |||:  |::.|
  Fly   448 QRVMTKIITKLKYTNIDLLANFGGIISLYIGASVMSFI-----ELLFVLGKLMWGFIRDARIKLK 507

  Fly   396 EQAK 399
            |..|
  Fly   508 EYTK 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	78/410 (19%)
ppk19	NP_651708.2	ASC	39..489	CDD:279230	84/435 (19%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079	4/22 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000