DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk17 and asic2

DIOPT Version :9

Sequence 1:	NP_001285988.1	Gene:	ppk17 / 35006	FlyBaseID:	FBgn0032602	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_005164179.1	Gene:	asic2 / 407669	ZFINID:	ZDB-GENE-040513-4	Length:	564	Species:	Danio rerio

Alignment Length:	500	Identity:	87/500 - (17%)
Similarity:	160/500 - (32%)	Gaps:	139/500 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 YLVLFACCIVVIV-----QLYECFAKLYNPPISTHSYYSLNETIEMPSVTICREPPYKEEVLTR- 79
            :::.|..|:.:::     :|....|.    |..|..:....:.:..|:||||...|.:...||:
Zfish    92 WMIAFCTCLGLLLSWSSNRLLHWLAF----PTHTRVHTEWAKELAFPTVTICNNNPVRLYHLTKS 152

  Fly    80 -----------LSGGACPHP---------------KYATCWMKYP---FGEISLDEFFENSTHDS 115
                       |.......|               |.:...:..|   |...|| ||.:...|..
Zfish   153 DLYFAGHWLGLLLANRTARPLVLDLLQDDRRGWFSKLSDFRLFLPPRRFEGTSL-EFMDRLGHQL 216

  Fly   116 GDTFVFYGLNEDKNNVVMNSSLHFYMGRCYTLRPKESAKRVSKAV------GYSIML----EHSM 170
            .|..:......:.......|::....|:||.....|..|.:...:      |..|||    :..:
Zfish   217 EDMLLACKYRGEPCGAHNFSTVFTRYGKCYMFNAAEEGKTLRTTMKGGTGNGLEIMLDIQQDEYL 281

  Fly   171 LTTSVSDVDTGSVGWHVFIHDKKE-------------NFTEINMKGSGRVEYVFVGVNEEIEIKL 222
            .....::......|..|.||.:.|             .|.........|:.|:.....|.:...|
Zfish   282 PVWGETEETAFEAGVRVQIHSQAEPPFVHELGFGVAPGFQTFVATQEQRLTYLPPPWGECVSRAL 346

  Fly   223 QTQYFSNVQTREEACSDDENYSDLKCGEQCIWQDLADNMQC-----------SGPWMHEIASEPC 276
            .:..|             :.||...|..:|..:.:.:|..|           ..|..::..:||.
Zfish   347 DSGLF-------------QVYSVSACRIECETRYIVENCNCRMVYMPGDSPYCTPEQYKDCAEPA 398

  Fly   277 NDSLSMRKLISDYKDVYENEDDFDCDCVQPCQSRIY------------TTFIQNRKAFNQPEPRT 329
            ..:||.             .:..:|.|..||....|            |:.....|.||:.|.
Zfish   399 LAALSA-------------VEGTNCICRSPCNMTRYNKELSMVKIPSKTSARYLEKKFNRSEK-- 448

  Fly   330 QIYIYYTTKLISM-----------IEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHMMLF 383
                |.|..::.:           ||::.:|:....:.|:||.:|..:|.|:|.|:.:.::....
Zfish   449 ----YITDNILVLDVFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTLLELFDYAYEV 509

  Fly   384 FCGGFIKRMQQKEQAKLEANSED--------GQSQTSDETIDVEI 420
            .....:..:.::|:.  |::.||        ..|::...|:.|.:
Zfish   510 VKERLLDLLNREEEE--ESHGEDVSTCDPVVNHSESISHTVSVPL 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	72/428 (17%)
asic2	XP_005164179.1	ASC	71..538	CDD:295594	84/484 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586628
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840