DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk17 and ppk25

DIOPT Version :9

Sequence 1:	NP_001285988.1	Gene:	ppk17 / 35006	FlyBaseID:	FBgn0032602	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_995766.1	Gene:	ppk25 / 2768722	FlyBaseID:	FBgn0053349	Length:	451	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	88/459 - (19%)
Similarity:	154/459 - (33%)	Gaps:	117/459 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YWSETRAWLFRDPAKLIRYLVLFACCIVVIVQLY----ECFAKLY----NPPISTHSYYSLNETI 59
            :|:|...|.|                 :::...|    .|..:.|    ||.:..:.|.......
  Fly    35 HWAERLFWTF-----------------IILGSAYYAISSCLNQWYRFRDNPIVYEYEYLFGLRIF 82

  Fly    60 EMPSVTICREPPYKEEV----LTRLSGGACP--HPKYATCWMKY-------PFGEISLDEFFENS 111
            ....:|:|  |.|.:|.    |...:.|..|  ..:.|..:.|:       .:..:...|.|||.
  Fly    83 PFVGITLC--PRYHDETEIPRLINQTWGVDPSEDKEKAVYYRKFLLAINGLRYSTLETLEPFEND 145

  Fly   112 THDSGDTFVFYGLNEDKNNVVM------------------NSSLHFYMGRCYTLRPKESAKRVSK 158
            |......::...|...|..:.:                  :|.|:.| |..|.....:..:.: |
  Fly   146 TTLDNVNYLNILLTLQKKVIAVKIPPELAPIITEVGLCQTSSQLNRY-GNPYGKLETQDMEPM-K 208

  Fly   159 AVGYSIMLEHSMLTTSVSDVDTGSVGWHVFIHDKKENFTEINMK----GSGRVEYVFVGVNEEIE 219
            ..||.     |...||:..:::......:::||.:|.....:|:    .:..:|      :::::
  Fly   209 QCGYL-----SNCITSLKPINSIVAPIFMYLHDVEEMMLPDDMRTPSFDAKDIE------SKDLD 262

  Fly   220 IKLQT----QYFSNVQTREEAC--SDDEN------YSDLKCGEQCIWQDLADNMQCSGPWMHEIA 272
            |.|.|    ....|:......|  ||:.|      |....|..:|..:.......|. |:.:..|
  Fly   263 IMLHTTSAESEVRNLPVAYRKCRFSDENNLQYYSPYHPSLCRLECRIKWALSLCNCK-PYFYVAA 326

  Fly   273 SEP--CNDS----LSMRKLISDYKDVYENEDDFDCDCVQPCQSRIYTTF---IQNRKAFNQPEPR 328
            .|.  |..|    |:..|.:           :..|||...|:...:|.|   .|.....|....|
  Fly   327 PEVPICTVSGMLCLARSKWL-----------ERPCDCYPSCREETFTIFKVSDQTGGDDNYSGER 380

  Fly   329 TQIYIYYTTKLISM-IEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHMMLF--------F 384
            .:..:....::..| |..|..:.|.|.|...||::|..||.|.:.:.|::...:.|        |
  Fly   381 FERTLIINLQISRMGINRRVVFSTDQLIMSFGGAIGLFLGASFMTIYGVVYFFLTFIAYTCKNRF 445

  Fly   385 CGGF 388
            |..|
  Fly   446 CKRF 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	74/411 (18%)
ppk25	NP_995766.1	ASC	18..432	CDD:279230	84/440 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000