DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ppk17 and Asic2

DIOPT Version :9

Sequence 1:NP_001285988.1 Gene:ppk17 / 35006 FlyBaseID:FBgn0032602 Length:431 Species:Drosophila melanogaster
Sequence 2:NP_037024.2 Gene:Asic2 / 25364 RGDID:2017 Length:563 Species:Rattus norvegicus


Alignment Length:479 Identity:86/479 - (17%)
Similarity:159/479 - (33%) Gaps:146/479 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 PISTHSYYSLNETIEMPSVTICREPPYKEEVLTRLSGGACPHPKYATCWM--------------- 95
            |..|..:...:..:..|:||:|...|.:   ..|||.|..   .||..|:               
  Rat   115 PSHTRVHREWSRQLPFPAVTVCNNNPLR---FPRLSKGDL---YYAGHWLGLLLPNRTARPLVSE 173

  Fly    96 --------KYPFGEISLDEFFENSTHDSGDTFVFYG-LNEDKNNVVMN-------------SSLH 138
                    :..|.:::....|....|..|.:..|.. |.....:::::             ||:.
  Rat   174 LLRGDEPRRQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPHNFSSVF 238

  Fly   139 FYMGRCYTLRPKESAKRVSKAV------GYSIML----EHSMLTTSVSDVDTGSVGWHVFIHDKK 193
            ...|:||.....|..|.:...|      |..|||    :..:.....::..|...|..|.||.:.
  Rat   239 TKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQS 303

  Fly   194 ENFTEINMKGSGRVEYVFVGVNEEIEIKLQTQYFSNVQTREE----------ACSDDEN------ 242
            |.              .|:   :|:...:...:.:.|.|:|:          .|...|.      
  Rat   304 EP--------------PFI---QELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEMGLDFFP 351

  Fly   243 -YSDLKCGEQCIWQDLADNMQC-----------SGPWMHEIASEPCNDSLSMRKLISDYKDVYEN 295
             ||...|...|..:.:.:|..|           ..|..|:..:||....|:            |.
  Rat   352 VYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLLA------------EK 404

  Fly   296 EDDFDCDCVQPCQSRIY------------TTFIQNRKAFNQPEPRTQ-----IYIYYTTKLISMI 343
            :.:: |.|..||....|            |:.....|.||:.|....     :.|::.......|
  Rat   405 DSNY-CLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETI 468

  Fly   344 EERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHM-------MLFFCGGFIKRMQQKEQAKLE 401
            |::.:|:....:.|:||.:|..:|.|:|.::.:.:::       :|...|      :::|:...:
  Rat   469 EQKKAYEVAALLGDIGGQMGLFIGASLLTILELFDYIYELIKEKLLDLLG------KEEEEGSHD 527

  Fly   402 AN-----SEDGQSQTSDETIDVEI 420
            .|     :....|:|...|::|.:
  Rat   528 ENMSTCDTMPNHSETISHTVNVPL 551

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ppk17NP_001285988.1 ASC 11..358 CDD:295594 71/403 (18%)
Asic2NP_037024.2 ENaC 64..557 CDD:273304 86/479 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166345655
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

Return to query results.
Submit another query.