Protein Alignment ppk17 and Asic2

DIOPT Version :10

• Sequence 1: NP_609809.1
• Gene: ppk17 / 35006
• FlyBaseID: FBgn0032602
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_037024.2
• Gene: Asic2 / 25364
• RGDID: 2017
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 86/479 - (17%)
• Similarity: 159/479 - (33%)
• Gaps: 146/479 - (30%)

  Fly    46 PISTHSYYSLNETIEMPSVTICREPPYKEEVLTRLSGGACPHPKYATCWM--------------- 95
            |..|..:...:..:..|:||:|...|.:   ..|||.|..   .||..|:
  Rat   115 PSHTRVHREWSRQLPFPAVTVCNNNPLR---FPRLSKGDL---YYAGHWLGLLLPNRTARPLVSE 173

  Fly    96 --------KYPFGEISLDEFFENSTHDSGDTFVFYG-LNEDKNNVVMN-------------SSLH 138
                    :..|.:::....|....|..|.:..|.. |.....:::::             ||:.
  Rat   174 LLRGDEPRRQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPHNFSSVF 238

  Fly   139 FYMGRCYTLRPKESAKRVSKAV------GYSIML----EHSMLTTSVSDVDTGSVGWHVFIHDKK 193
            ...|:||.....|..|.:...|      |..|||    :..:.....::..|...|..|.||.:.
  Rat   239 TKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQS 303

  Fly   194 ENFTEINMKGSGRVEYVFVGVNEEIEIKLQTQYFSNVQTREE----------ACSDDEN------ 242
            |.              .|:   :|:...:...:.:.|.|:|:          .|...|.
  Rat   304 EP--------------PFI---QELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEMGLDFFP 351

  Fly   243 -YSDLKCGEQCIWQDLADNMQC-----------SGPWMHEIASEPCNDSLSMRKLISDYKDVYEN 295
             ||...|...|..:.:.:|..|           ..|..|:..:||....|:            |.
  Rat   352 VYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLLA------------EK 404

  Fly   296 EDDFDCDCVQPCQSRIY------------TTFIQNRKAFNQPEPRTQ-----IYIYYTTKLISMI 343
            :.:: |.|..||....|            |:.....|.||:.|....     :.|::.......|
  Rat   405 DSNY-CLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETI 468

  Fly   344 EERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHM-------MLFFCGGFIKRMQQKEQAKLE 401
            |::.:|:....:.|:||.:|..:|.|:|.::.:.:::       :|...|      :::|:...:
  Rat   469 EQKKAYEVAALLGDIGGQMGLFIGASLLTILELFDYIYELIKEKLLDLLG------KEEEEGSHD 527

  Fly   402 AN-----SEDGQSQTSDETIDVEI 420
            .|     :....|:|...|::|.:
  Rat   528 ENMSTCDTMPNHSETISHTVNVPL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_609809.1	ASC	22..358	CDD:459966	71/403 (18%)
Asic2	NP_037024.2	ENaC	64..557	CDD:273304	86/479 (18%)