Protein Alignment ppk17 and Scnn1a

DIOPT Version :10

• Sequence 1: NP_609809.1
• Gene: ppk17 / 35006
• FlyBaseID: FBgn0032602
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 105/524 - (20%)
• Similarity: 163/524 - (31%)
• Gaps: 203/524 - (38%)

  Fly    21 YLVLFACCIVVIVQLYECFAKLYNP----PISTHSYYSLN-ETIEMPSVTICREPPY-----KEE 75
            :.||:.|   ....:|..||.|:..    |:|.:  .:|| :.:..|:||:|...||     |||
  Rat   113 WAVLWLC---TFGMMYWQFALLFEEYLSYPVSLN--INLNSDKLVFPAVTVCTLNPYRYTEIKEE 172

  Fly    76 V--------------------LTRLSG----------GACPHPKYATCWMKYPF-------GEIS 103
            :                    .||.:|          ||.|||.........|:       |..|
  Rat   173 LEELDRITEQTLFDLYKYNSSYTRQAGARRRSSRDLLGAFPHPLQRLRTPPPPYSGRTARSGSSS 237

  Fly   104 L------------------------DEFFENSTHDSG--------------------DT------ 118
            :                        |.|::  |:.||                    ||
  Rat   238 VRDNNPQVDRKDWKIGFQLCNQNKSDCFYQ--TYSSGVDAVREWYRFHYINILSRLSDTSPALEE 300

  Fly   119 -----FVF-YGLNEDKNNVVMNSSLHFYM-GRCYTLRPK-------ESAKRVSKAVGYSIMLEHS 169
                 |:| ...|:...|....|..|..| |.|||...|       .|...|:..:..::..|.:
  Rat   301 EALGNFIFTCRFNQAPCNQANYSKFHHPMYGNCYTFNDKNNSNLWMSSMPGVNNGLSLTLRTEQN 365

  Fly   170 MLTTSVSDVDTGSVGWHVFIHDKKENFTEINMKGSGRVEYVFV---GVNEEIEIKLQTQYFSNVQ 231
            .....:|.|    .|..|.:|              |:.|..|:   |.|      |:....:::.
  Rat   366 DFIPLLSTV----TGARVMVH--------------GQDEPAFMDDGGFN------LRPGVETSIS 406

  Fly   232 TREEA----------CSDDENYSDL--------KCGEQ-CIWQDLADNM--QCSGPWM---HEIA 272
            .|:||          |:  ||.||:        |..:| ||.....:||  :|...::   ....
  Rat   407 MRKEALDSLGGNYGDCT--ENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAYIFYPKPKG 469

  Fly   273 SEPCNDSLSMRKLISDYKDVYENEDDFDCD-------CVQPC-------------------QSRI 311
            .|.|:    .||..|.....|:.:..|..|       |.:||                   |..|
  Rat   470 VEFCD----YRKQSSWGYCYYKLQGAFSLDSLGCFSKCRKPCSVINYKLSAGYSRWPSVKSQDWI 530

  Fly   312 YTTF-IQNRKAFNQPEPR-TQIYIYYTTKLISMIEERPSYDTTQFIADVGGSLGFLLGLSVLGLI 374
            :... :||....|..... .::.|::.........|.||......::::|.......|.|||.::
  Rat   531 FEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSESPSVTMVSLLSNLGSQWSLWFGSSVLSVV 595

  Fly   375 GILE 378
            .:.|
  Rat   596 EMAE 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_609809.1	ASC	22..358	CDD:459966	99/501 (20%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	105/524 (20%)