Protein Alignment ppk17 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001285988.1
• Gene: ppk17 / 35006
• FlyBaseID: FBgn0032602
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 98/546 - (17%)
• Similarity: 168/546 - (30%)
• Gaps: 208/546 - (38%)

  Fly    23 VLFACCIV----VIVQLYECFAKLYNPPISTHSYYSLN---ETIEMPSVTICREPPYK------- 73
            :||||.:.    |.:|.|          :|.....||:   :|:..|:||:|...|::
  Rat    57 LLFACLVCWQWGVFIQTY----------LSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHL 111

  Fly    74 --------EEVLTRLSGGACPHPKYA-----TCWMKYPFGEISLDE----------FFENSTHDS 115
                    |.||.::......|....     |.|...|.  :.:||          .|.:| |:|
  Rat   112 LKDLYKLMEAVLDKILAPKSSHTNTTSTLNFTIWNHTPL--VLIDERNPDHPVVLNLFGDS-HNS 173

  Fly   116 GD----------------------------------------------TFVF--------YGLNE 126
            .:                                              |.:|        .|:..
  Rat   174 SNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGY 238

  Fly   127 DKNNVVM------------NSSLHFY--MGRCYTLRPKESAKRVSKA-----VGYSIMLEHSMLT 172
            ..:.:::            |.:..||  .|.||......:.|.:..|     .|..::|:
  Rat   239 APDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILD----- 298

  Fly   173 TSVSDVD-----TGSVGWHVFIHDKKENFTEINMKGSGRVEYVFVGVNEEIEI---KLQ------ 223
              :...|     ..:.|..:.:|::: .:..|..:|.    |...|....|.:   |||
  Rat   299 --IGQEDYVPFLASTAGARLMLHEQR-TYPFIREEGI----YAMAGTETSIGVLLDKLQGKGEPY 356

  Fly   224 ---TQYFSNVQTREEACSDDENYSDLKCGEQCIWQDLADNMQCS------------------GPW 267
               |...|:|..:......:..||...|...|....:..|..|.                  ..|
  Rat   357 SPCTMNGSDVAIQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPDW 421

  Fly   268 MH----------------EIASEPCNDS-LSMRKLISDYKDVYENEDDFDCDCVQPCQSRIYTTF 315
            .:                .:..|.|||: ..|...::|:..  |..:|:....:.  |.|..::.
  Rat   422 AYCYLSLQMSVVQRETCLSMCKESCNDTQYKMTISMADWPS--EASEDWILHVLS--QERDQSSN 482

  Fly   316 IQ-NRKAFNQPEPRTQIYIYYTTKLISMIEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEH 379
            |. :||..      .::.||:.......|||.|:.:....::::||..||.:|.|||.||...|.
  Rat   483 ITLSRKGI------VKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEI 541

  Fly   380 MMLFF----------CGGFIKRMQQK 395
            ::.|.          |.|..:|..|:
  Rat   542 IIDFIWITVIKLVASCKGLRRRRPQR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	82/497 (16%)
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	98/546 (18%)
		deg-1	29..538	CDD:273309	92/515 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345645
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830