Protein Alignment ppk17 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001285988.1
• Gene: ppk17 / 35006
• FlyBaseID: FBgn0032602
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001258952.1
• Gene: Scnn1b / 20277
• MGIID: 104696
• Length: 638
• Species: Mus musculus
• Alignment Length: 548
• Identity: 99/548 - (18%)
• Similarity: 171/548 - (31%)
• Gaps: 214/548 - (39%)

  Fly    23 VLFACCIV----VIVQLYECFAKLYNPPISTHSYYSLN---ETIEMPSVTICREPPYK------- 73
            :||||.:.    |.:|.|          :|.....||:   :|:..|:||:|...|::
Mouse    57 LLFACLVCWQWGVFIQTY----------LSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHL 111

  Fly    74 --------EEVLTRLSGGACPHPKYA-----TCWMKYPFGEISLDE----------FFENSTHDS 115
                    |.||.::......|....     |.|...|.  :.:||          .|.:| |:|
Mouse   112 LKDLDELMEAVLEKILAPEASHSNTTRTLNFTIWNHTPL--VLIDERNPDHPVVLNLFGDS-HNS 173

  Fly   116 GD----------------------------------------------TFVF--------YGLNE 126
            .:                                              |.:|        .|:..
Mouse   174 SNPAPGSTCNAQGCKVAMRLCSANGTVCTLRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGY 238

  Fly   127 DKNNVVM------------NSSLHFY--MGRCYTLR---PKESAKRVSKAVGYSIMLEHSMLTTS 174
            ..:.:::            |.:..||  .|.||...   .:|:....:....:.:.|
Mouse   239 APDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEETLPSANPGTEFGLKL-------- 295

  Fly   175 VSDVD--------TGSVGWHVFIHDKKENFTEINMKGSGRVEYVFVGVNEEIEI---KLQ----- 223
            :.|:.        ..:.|..:.:|::: .:..|..:|.    |...|....|.:   |||
Mouse   296 ILDIGQEDYVPFLASTAGARLMLHEQR-TYPFIREEGI----YAMAGTETSIGVLVDKLQRKGEP 355

  Fly   224 ---------------------TQYFSNVQTREEACSDDENYSDLKCG----------EQCIWQDL 257
                                 |.|  ::|....:|..|....:..||          :.|..:|.
Mouse   356 YSPCTMNGSDVAIKNLYSVYNTTY--SIQACLHSCFQDHMIRNCSCGHYLYPLPEGEKYCNNRDF 418

  Fly   258 AD------NMQCSGPWMH---EIASEPCNDS-LSMRKLISDYKDVYENEDDFDCDCVQPCQSRIY 312
            .|      |:|.|.....   .:..|.|||: ..|...::|:..  |..:|:....:.  |.|..
Mouse   419 PDWAYCYLNLQMSVTQRETCLSMCKESCNDTQYKMTISMADWPS--EASEDWILHVLS--QERDQ 479

  Fly   313 TTFIQ-NRKAFNQPEPRTQIYIYYTTKLISMIEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGI 376
            ::.|. :||..      .::.||:.......|||.|:.:....::::||..||.:|.|||.||..
Mouse   480 SSNITLSRKGI------VKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEF 538

  Fly   377 LEHMMLFF----------CGGFIKRMQQ 394
            .|.::.|.          |.|..:|..|
Mouse   539 GEIIIDFIWITIIKLVASCKGLRRRRPQ 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	83/500 (17%)
Scnn1b	NP_001258952.1	ENaC	21..621	CDD:273304	99/548 (18%)
		deg-1	29..538	CDD:273309	93/518 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	594..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842215
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830