Protein Alignment ppk17 and asic-2

DIOPT Version :10

• Sequence 1: NP_609809.1
• Gene: ppk17 / 35006
• FlyBaseID: FBgn0032602
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 105/523 - (20%)
• Similarity: 179/523 - (34%)
• Gaps: 155/523 - (29%)

  Fly    34 QLYECFAKLYNPPISTHSYYSLNETIEMPSVTICREPPYKEEVLTRLSGGACPHPKYATCWMKYP 98
            :||...||.::.|.:.::.....:.| .|.||:|...|||..|:...|..:..: ...|.:....
 Worm    51 ELYILIAKFFSYPATVNTEILFEKQI-FPVVTVCNMNPYKYSVVKSNSAFSSVN-TLMTTYSDAT 113

  Fly    99 FGEISLDE---FFEN-STHD----SGDTFVFYGLNEDKNNVVMNS----SLHFY----------- 140
            .|..|.|:   :.:| .|:|    :.|..|.      :.|::.::    :|:.|
 Worm   114 VGTFSTDKWGLYADNDETYDLDSRAADALVL------EANLISDTAKVPALYTYADLIQDCSFAG 172

  Fly   141 ---------------MGRCYTLRP----KESAKRVSKAVGYSIML----------EHSMLTTSVS 176
                           .|.||:...    ..|..|.....|..:||          ..|:.||.::
 Worm   173 IPCSESDFTKFIDPVYGACYSFNEDASLNYSVSREGIQFGLKLMLTVTQTKTNGNTDSLPTTKLA 237

  Fly   177 DVDTGSVGWHVFIHDKKENFTEINMKGS-------------GRVEYVFVGVNEEIEIKLQTQYFS 228
            ....|                 :|.:||             |....|.|.:.:.:..|   :.:.
 Worm   238 GARIG-----------------VNSRGSSPGLDSNGIDAGVGYESAVSVSLTQNVRAK---KPYG 282

  Fly   229 NVQTREEACSD---DENYSDLKCGEQCIWQDLADNMQCSGPWM----HEIASEPCNDSLS-MRKL 285
            ....||...||   |..|:...|...|..:|.....||:.|.:    .:.|.:|....|. ::.|
 Worm   283 TCVDREPDSSDYYKDFIYTLETCFNGCKQRDTIAKCQCANPRLALGSTDTACQPIKADLDCLQTL 347

  Fly   286 ISDYKDVYENEDDF-DCDCVQPCQSRIYTTFIQ-------------------------NRKAFNQ 324
            ..:......|.|.. :|:|..||....||..:.                         |.|..::
 Worm   348 KGNQTSSTPNIDLLVECNCNPPCDESTYTPTVSLAQFPSTSYYVATSSTAGVGSCSSTNSKFSSK 412

  Fly   325 PEPRTQ-------IYIYYTTKLISMIEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHMML 382
            .:.:..       |.::..|....:..|...|..:..|.|:||..|..|||||:.::.:...|::
 Worm   413 SDCQKWYNNNGMIIQVFLETLSYELYTETAGYTVSNVINDLGGQAGLWLGLSVISVVEMTGLMLV 477

  Fly   383 F--FC--GGFIK------------RMQQKEQAKLEAN---SEDGQSQT-SDETIDVEIAYKKKEK 427
            .  ||  ||.||            |::..|..|.|.:   .:.|:.:: ||..:| :|..|..|:
 Worm   478 MGAFCVTGGAIKMAPDDDEIENDHRIKDVEDVKKEIDHLEKKHGEMESGSDGEVD-DIENKGDEE 541

  Fly   428 QPK 430
            :.|
 Worm   542 KKK 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_609809.1	ASC	22..358	CDD:459966	77/429 (18%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	86/450 (19%)