DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk17 and degt-1

DIOPT Version :9

Sequence 1:	NP_001285988.1	Gene:	ppk17 / 35006	FlyBaseID:	FBgn0032602	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_505703.3	Gene:	degt-1 / 184921	WormBaseID:	WBGene00009109	Length:	852	Species:	Caenorhabditis elegans

Alignment Length:	349	Identity:	65/349 - (18%)
Similarity:	127/349 - (36%)	Gaps:	110/349 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RYL---------VLFACCIVVIVQL--YECFAKL----YNPPISTHSYYSLNETIEMPSVTICRE 69
            |||         ||:...:|..:.|  |:.|.::    ...|::|...|.....:..|::.:|.:
Worm    54 RYLHTRYKTWFRVLWGFVVVFFIGLTFYQVFERVTYYFIKNPLTTRRSYETLPNMYFPTIGVCNK 118

  Fly    70 PPYKE---------------EVLTRLSGGACPHPKYATCWMKYPFGEISLDEFFENSTHDSGDTF 119
            ...|.               .||...|..:....:..      .|.::.:...:.||...:.|.|
Worm   119 MQIKASSVASKNPDLLRGMCSVLDESSSNSSRFDELD------KFDDVDILSLYRNSFQSADDLF 177

  Fly   120 VF--YGLNEDKNNVVMNSSLHFY--MGRCYTLRPKESAKRVSKAVGYSIMLE---HSMLTTSVSD 177
            |.  :|    |:....:.....|  .|.||::.|.::..|.......|::|.   |.::..:|
Worm   178 VSCEFG----KSGSCQDEIRPIYTPFGLCYSVSPNKTILRPGPETTLSLVLNLEVHEIIPGTV-- 236

  Fly   178 VDTGSVGWHVFIHDKKENFTE----INMKGSGRVEYVFVGVNEEIEIKLQTQYFSNVQTREEACS 238
            |:.|.|   :.|:|...:.:.    |::: :|:|  |.:.|||..:::|          .|.:|.
Worm   237 VEPGVV---LSIYDGASSLSHYSEGIHLE-AGKV--VTIPVNEVRKLRL----------HESSCG 285

  Fly   239 DD--ENYSDLKCGEQCIWQDLADNMQCSGPWMHEIASEPCNDSLSMRKLISDYKDVYENEDDFDC 301
            ..  |::|:                       .|.:...|..|:|::::            :.:|
Worm   286 STKMESFSE-----------------------KEYSKAACEWSVSVKQI------------EKEC 315

  Fly   302 DCVQPCQSRIYTTFIQNRKAFNQP 325
            .|: |.::.||.....|:   |.|
Worm   316 GCI-PIRNPIYRGVFDNK---NDP 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	65/349 (19%)
degt-1	NP_505703.3	ASC	44..>318	CDD:279230	58/326 (18%)
degt-1	NP_505703.3	ASC	<704..836	CDD:295594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900