DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BuGZ and znf-207

DIOPT Version :9

Sequence 1:	NP_001260513.1	Gene:	BuGZ / 35004	FlyBaseID:	FBgn0032600	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_502124.1	Gene:	znf-207 / 178042	WormBaseID:	WBGene00007105	Length:	341	Species:	Caenorhabditis elegans

Alignment Length:	340	Identity:	131/340 - (38%)
Similarity:	159/340 - (46%)	Gaps:	79/340 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRKKKKASKPWCWYCNREFDDEKILVQHQKAKHFKCHICHKKLYTGPGLSIHCMQVHKETVDKV 65
            |||||||..|||||||||||||||||:|||||||||||||||||::|||||||||||||||:||:
Worm     1 MGRKKKKVDKPWCWYCNREFDDEKILIQHQKAKHFKCHICHKKLFSGPGLSIHCMQVHKETIDKI 65

  Fly    66 PNSLPNRSNIEVEIFGMDGIPAEDLRDHERQKNGGKSDSDDDEPVAKKKVEYAMSVPPPMMMPPN 130
            |.::..|.||.|||:||.|||:...|        |.:|.:.||  .:.:::....:|.||..|.:
Worm    66 PAAVHGRDNIHVEIYGMQGIPSGAYR--------GAADEEPDE--KRSRMDNGPPMPTPMPFPQH 120

  Fly   131 M----MPPHMLG------QYGM-----GMM-------QHMPP--LPPYPVP---MMPHMMP---P 165
            .    |||...|      .|||     |||       .:.||  .||.|.|   |.|..||   |
Worm   121 FPFPGMPPMPSGPPPPSMAYGMPPMPSGMMPPRGMPGAYPPPRGYPPAPAPGVYMPPPGMPGAYP 185

  Fly   166 RPLFPAAMATTSAAAAAAAAHHHHA---------AAMAQQKPTFPAYSN----ATISAPPTTNHA 217
            .|..|....................         ....:..|..|.|.|    ....||...|..
Worm   186 PPRMPIGHGPPGGPPMPGPPQRSRFDQPDGGDRWGPPMRGVPRTPPYENEHEHQDYQAPDDYNQG 250

  Fly   218 G-------GASSAPPSG----------PPDAQQHQQRPPAPPA-ASGTSAAAVT-------TKIM 257
            |       |....||.|          ..:..:....||...: |:..|||||.       |:|:
Worm   251 GYDDRFREGDRGGPPGGSRFDQVKAELKEEIVEPNNGPPTTSSGAAAASAAAVVASKLGSRTRIV 315

  Fly   258 HPQE-DLSLEELRAR 271
            :|.: .|||||.|.:
Worm   316 YPDDHSLSLEERRVK 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BuGZ	NP_001260513.1	C2H2 Zn finger	13..32	CDD:275368	17/18 (94%)
		C2H2 Zn finger	37..58	CDD:275368	18/20 (90%)
		PABP-1234	<479..607	CDD:130689
znf-207	NP_502124.1	C2H2 Zn finger	13..32	CDD:275368	17/18 (94%)
znf-207	NP_502124.1	C2H2 Zn finger	37..58	CDD:275368	18/20 (90%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2710
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004631
OrthoInspector	1	1.000	-	-		oto20472
orthoMCL	1	0.900	-	-		OOG6_102795
Panther	1	1.100	-	-	LDO	PTHR23215
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4116
SonicParanoid	1	1.000	-	-		X3245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.980