Protein Alignment ChLD3 and lgx-1

DIOPT Version :9

• Sequence 1: NP_609806.1
• Gene: ChLD3 / 35002
• FlyBaseID: FBgn0032598
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001360720.1
• Gene: lgx-1 / 180825
• WormBaseID: WBGene00002983
• Length: 1754
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 170/559 - (30%)
• Similarity: 256/559 - (45%)
• Gaps: 108/559 - (19%)

  Fly    82 TSGAASCMQDARFYRNPNRPVHKIWTNSEC----AKYFL------CLDGEVFEFKCSEGLLFD-- 134
            |:|...|            |.:.|..|.:|    .|:.:      |.:||:    |:.|.:.|
 Worm  1236 TNGFCHC------------PENYIRQNGQCISKECKHKVAKVGETCKNGEI----CAGGSICDYD 1284

  Fly   135 -----------VVRQICD------FKANVDNCDVSAETPAPKPLLE-MADCADEYQLGCADGTCL 181
                       .:|.||.      |.|..|.|.:..:........| |..|.|.:  ...||.|.
 Worm  1285 RKRCICAAQHVAIRGICKQKSAPAFAAPGDTCSMREKCTGGATCFEGMCTCDDHH--FAEDGYCR 1347

  Fly   182 PQE------YFCDG------SVDCPDGSDEGWCDVEHDPNAAGACDPRKCHLPQCFCSKDGTQIP 234
            |.|      .|.:|      |:..|            :...|.||:..:|.||.|||:::|.:.|
 Worm  1348 PIEARSSKVQFVNGAGLRFSSMQVP------------NRQRAQACNEAECKLPNCFCTENGRRAP 1400

  Fly   235 GSLPAQSVPQMILLTFDDAINHDNWELFSKVLFTQHRRNPNGCPIKGTFYVSHPFTNYQYVQKLW 299
            |.|.....||.::||||||:|...:..:.|:......:|||||.:|.||::||.:|||..|..|.
 Worm  1401 GGLRPDETPQFVVLTFDDAVNGKTFSDYKKLFENDVLKNPNGCDVKATFFISHEWTNYDAVNWLV 1465

  Fly   300 NDGHEIAVHSVTHRGPEMWWSKNATIEDWFDEMVGQANIINKFAAVRMEEIRGMRVPFLRVGWNR 364
            ....|||.:|::|...|     ||....|.:||.||..|:.||.....|||.|:|.|.|.:|.:.
 Worm  1466 QKNMEIASNSISHESLE-----NANTNRWLNEMDGQRRILAKFGGAPEEEIVGIRSPQLALGGDN 1525

  Fly   365 QFLMMKEFGFVYDSSMVAPHSNP-----PLWPYTLDYKMPHSCTGVNQNCPSRSYPGIWELVMNQ 424
            ||.||....|::|:||.|   ||     |.||.|:||::...|.  ..:||..|:||:|.:.:||
 Worm  1526 QFEMMIGAEFLWDNSMSA---NPGIHGEPFWPQTMDYQVAWDCN--EASCPKSSFPGVWSVPLNQ 1585

  Fly   425 LEVGEYMCGMVDT--------CPPHLSG--EDVYRMLTHNFKRHYLSNRAPFGLYFHSTWFKKVD 479
            . .|.|| ..:|:        ....|:.  :::..::|.||:|.|.:||||:.|..::.:.:...
 Worm  1586 F-YGSYM-SQIDSFRRSSMLRAAVDLNNTVDELEEIITRNFERSYSANRAPYVLSLNADFLQLGG 1648

  Fly   480 Y---LNAFLKFLDDLQKLPDVFFVTNQQAIQWMRHPTPSNQLHQFESWHCQPKDL----DPHEQV 537
            :   :.|..|||:.:....||:.||.:|.|.||:.|.|.:::...::..| |..|    :|....
 Worm  1649 HNKGMKAVQKFLNRMSAQKDVYIVTIKQLIDWMKRPVPISEMKSSKAVGC-PITLSFNRNPSLST 1712

  Fly   538 CNTPNVCKVRSRVL-QEDRFFYTCMECPAQYPWIRNEFG 575
            |:.||.|...:..| .::..|.||:.||..|||:.|..|
 Worm  1713 CDIPNKCLYSTPSLSSQEHQFLTCLPCPTMYPWLENPAG 1751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChLD3	NP_609806.1	CBM_14	<111..149	CDD:279884	14/66 (21%)
		LDLa	168..202	CDD:238060	10/45 (22%)
		CE4_CDA_like_1	243..512	CDD:200596	102/286 (36%)
lgx-1	NP_001360720.1	EB	322..382	CDD:366756
		PHA02682	<388..>493	CDD:177464
		EB	565..620	CDD:366756
		EB	609..666	CDD:366756
		EB	<718..757	CDD:366756
		EB	911..967	CDD:366756
		EB	956..1020	CDD:366756
		EB	1009..1083	CDD:366756
		EB	1072..1124	CDD:366756
		EB	<1215..1253	CDD:366756	6/28 (21%)
		EB	1242..1301	CDD:366756	13/74 (18%)
		EB	1290..1346	CDD:366756	13/57 (23%)
		CE4_CDA_like_1	1409..1684	CDD:200596	102/286 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4700
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003270
OrthoInspector	1	1.000	-	-		otm14253
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.010