DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment glu and EMC10

DIOPT Version :9

Sequence 1:	NP_723996.1	Gene:	glu / 35001	FlyBaseID:	FBgn0015391	Length:	1409	Species:	Drosophila melanogaster
Sequence 2:	NP_730662.2	Gene:	EMC10 / 40396	FlyBaseID:	FBgn0052441	Length:	227	Species:	Drosophila melanogaster

Alignment Length:	156	Identity:	37/156 - (23%)
Similarity:	63/156 - (40%)	Gaps:	36/156 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   460 TLNEELEK-QQAELTKTTAPLTEKRLKLSDELVGLKEKV---NTAKGEVQVFESQLKILKQAE-- 518
            :||..|.. :|.:|:.....|. |:|.|.:|...||..|   |.||.:........::| ||:
  Fly    54 SLNSGLANVEQPDLSTADLDLL-KKLALGNEFYRLKATVVYSNGAKAQFITSNKACRLL-QAQLN 116

  Fly   519 -----TTESRKYET-LKSSYEQSQKSLEEKVTRVDELKESIPRMKTEIASKSAEVD--------- 568
                 :.|...|.| :..|.:.:..::|.....|::|.|:  :..|::..:.||:.
  Fly   117 DVLWVSLEPSGYVTGITVSQDTAPATIECTQEDVNKLLET--QFSTDVLIRHAELAPVPDTAGFI 179

  Fly   569 KMVKEERNLSMQCNKLRTEINERSSV 594
            :.|:.||           |..||..|
  Fly   180 QKVERER-----------EARERGEV 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
glu	NP_723996.1	ABC_SMC4_euk	87..>246	CDD:213241
		Smc	89..1281	CDD:224117	37/156 (24%)
		SMC_hinge	618..733	CDD:214944
		ATP-synt_B	<825..904	CDD:304375
		ABC_SMC4_euk	<1196..1290	CDD:213241
EMC10	NP_730662.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1196
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900