Protein Alignment glu and smc6

DIOPT Version :9

• Sequence 1: NP_723996.1
• Gene: glu / 35001
• FlyBaseID: FBgn0015391
• Length: 1409
• Species: Drosophila melanogaster
• Sequence 2: XP_031758814.1
• Gene: smc6 / 100495796
• -ID: -
• Length: 1122
• Species: Xenopus tropicalis
• Alignment Length: 1389
• Identity: 267/1389 - (19%)
• Similarity: 531/1389 - (38%)
• Gaps: 384/1389 - (27%)

  Fly    16 GARQSGQFRVPQLTAQQQLRAQQQQEEEDAAVDALDDALIFDDEEGGTRIGDIYIPPPVPPHC-- 78
            |.|:.|....|     ...|.:::||.|..          :|.|....:.|     |.|...|
 Frog     2 GKRKEGSPIAP-----NSQRKKERQEAEGT----------YDYEGDNVQAG-----PSVSNDCAH 46

  Fly    79 ------------------------SMESTGPRLIISKIVNRNFKSYAGEVELGPFH--QSFTAII 117
                                    |...||...||..|..|||..::   .||||.  .:...::
 Frog    47 HREPRDEANNSHTDRNYGNSVSCDSQSCTGEVGIIESISLRNFMCHS---MLGPFRFGPNVNFVV 108

  Fly   118 GPNGSGKSNVIDSMMFVFGCRANRIRCKRVSTLIHSSSSYPNLRSCSVAVHFKQIVDKG-DGTCE 181
            |.||||||.::.:::...|.:|  ....|.||:........|....|:.:.     ::| |....
 Frog   109 GNNGSGKSAILTALIVGLGGKA--AFTNRGSTIKGFIKGGENFAEISITLR-----NRGQDAYKP 166

  Fly   182 DVPDSSIVIERTAMSDNSSYYQ--------INDKRAQLKDVAKLLKKHHVDLEHNRFLILQGEVE 238
            ||..:||.:.:...::....|:        |::|:.:|   ..:|...::.:: |...:|..|:.
 Frog   167 DVFGNSITVRQRITTEGGRTYKLKSATGAVISNKKEEL---TMILDHFNIQVD-NPVSVLTQEMS 227

  Fly   239 SIAMMKPKGQTENETGMLEYLEDIVGTQRYIRPLQQINQRVDQLTDDRTEKHNRCKLAEREMKDL 303
            .:.:     |::||:...::.  :..||     |:|:.:....:.:.:::.|::.|:....:.||
 Frog   228 KLFL-----QSKNESDKYKFF--MKATQ-----LEQMKEDYSYIMETKSKTHDQVKIGSERLCDL 280

  Fly   304 EQPFNEAVDYLKKENELVRTKSFHIQKIISIKKSKLEQYTQEHEACAEELKTHDEGTAALKQSRA 368
            .|      |.::||      :||:....:...|..|:.                     ||.|.|
 Frog   281 RQ------DCIQKE------ESFNSIASLGEMKMNLDN---------------------LKNSMA 312

  Fly   369 EKETIIRKEIEEYEALVKKREQIK---KRLVTVESAYTEIQSTMENTNKQRKKDKAQIEKNEKEL 430
                        :..:::..:|||   .::||
 Frog   313 ------------WALVIEAEKQIKPIRDQIVT--------------------------------- 332

  Fly   431 EDLHKLPEKNQREIEDCNKKLESLEVSKVTLNEELEKQQAELTKTTAPLTEKRLKLSDELVGLKE 495
            |:.|.:  |.::.|::|..|:...|.......|||:|    :|:..|.|..|.:.|.|::...::
 Frog   333 EEGHTV--KYEQRIDECQGKVNIAEEKFRAKQEELDK----ITQEAAELKPKVIALKDDVQKKRK 391

  Fly   496 KVNTAKGEVQVFESQLKILKQAETTE---SRKYETLK----SSYEQSQKSLEEKVTRVDELKESI 553
            ..|.|:..   :..|:..||::|...   |::.|.||    ::.|:.:.:.::::.::.|.||.:
 Frog   392 SYNDAEAS---YNRQIMELKRSEKDAEQLSKRIEELKKRDGNASEREKMARQQEIAQITERKEEL 453

  Fly   554 PRMKTEIASKSAEVDKMVKEERNLSMQCNKLRTEINERSSVMQAQRSNNKVLDFLM-----RMKM 613
            ......|:.|..::.:.:::.:.     ..:|.| ||..:|.|....:.:.|..|.     |:|.
 Frog   454 QNHDITISQKIKQLQEAIEKHKE-----KWIRIE-NEEQNVKQRLEQHKRQLRELHESKTDRLKR 512

  Fly   614 EGK-IPGI---------LGR-----LGDLGG-IDAK-YDIAISTAC---GRLDNIVTDNYETASA 658
            .|| ||.:         |||     .|.||. |..| .::|::..|   |.|.....||::....
 Frog   513 FGKNIPSLLAAIDEAYNLGRFRKKPFGPLGAYIHLKDQELALAVECCLKGLLFAFCCDNHQDEGI 577

  Fly   659 AIGAL-KEYNVGRATFITLDKIEHHRREANSRINTPENVPRLYDLVKVEDDRVRTAF--YFALRN 720
            ....: |:|:.||...|.:.:..::..:.:.|.:...|.|.:...::::...|....  ...:..
 Frog   578 LQNIMSKQYSQGRRPQIIVSEFWNNVYDVSQRASFHPNHPTVLTALEIDHPVVANCLIDMRGIET 642

  Fly   721 TLVCDDLEQGTRIAYGRERYRVVTLRGEMIEMTGTMSGGGSRPIRGKMGTQVRTKTAESADSSQI 785
            .|:..|..:...|...|     |..|......||.             |.||.|....|:|:.:.
 Frog   643 ILIIKDKTEAREIMQKR-----VPPRNCREAFTGE-------------GDQVYTNRYYSSDTRRA 689

  Fly   786 SQKALEDMQIQAEELQARVNYCQEQQGSLEREIQTLKNGLQRDEAEYKRLAVSITSLEQQMASNL 850
            :        :.:.:::|.:::.:|:......::.||:.              |:.|:::.
 Frog   690 T--------LLSRDVEAEISHLEEELRDFGGQVATLQQ--------------SVHSVDKD----- 727

  Fly   851 KQCEAQRQRMLKKTTDERAVKEREEQIEAAKQELEQAQFAEQAVSSQIEEIQNQYD-------TL 908
                               :||.|:.:.......:|.|...:.:|.||.|::|..:       ||
 Frog   728 -------------------IKENEDNLRKYYNSKKQIQTELRTLSEQIAELENVEEQPSTDIATL 773

  Fly   909 RNESVKPVEAKIKKVNSQIEKLAANVRSLNVGLATADRNITKITGNNNNLRENIKAAEEKLKSLN 973
            ..|:.:..|. |:.|..::|....|:.:|.:.|.||:.|..:|              :.|:.|::
 Frog   774 EKEAAENTEI-IELVKQEVELAQENMGNLKLLLTTAESNYEEI--------------KRKIISVS 823

  Fly   974 EDRNKAKEKKEELEKEIEESEAS----IEGAKSQSSDIKKEIDEITKEENKRNI----------E 1024
            :.....||....:::|:|..:..    ::..|.....|:|..:|:..:|.:..:          |
 Frog   824 DVAEPVKEDLHRIDQEVENCKRHKKHYVDKLKKHLDRIQKRKEEVAGKEQELEVKISQAKYICPE 888

  Fly  1025 RIEIDTKLQAAAGKMNKVKNDIPGWQAQLAPLKLNEIPGETEPQAPLKEL---NEEELEAETLEA 1086
            |||:....::...::|:::.            |:|.           :|:   |.||:..:..||
 Frog   889 RIEVSRTARSLDTEINRLRE------------KINS-----------EEVLHGNREEIIMQYYEA 930

  Fly  1087 LQYKQTMLEEDLKTKKPNLSCIKEFNEKRLVYLDR-VRVLEDITSKRNEMRDKYEEVRKRRYKEF 1150
            .:..|..                   |:::.:|:| :.:|:.|..:|:|...|::.....|.|.|
 Frog   931 KERYQDA-------------------ERKIKHLNRFITLLDTIMEQRHECFQKFQRSLTLRCKCF 976

  Fly  1151 MDGFSIITRKLKEMYQMITLGGDAELELVDSMDPFTEGVNFTVRPPKKSWKYIS---NLSGGEKT 1212
               |:.:..:.|...::             :.|...|.::.||:|.:.:...:|   :|||||::
 Frog   977 ---FNSLLSQRKHSGKI-------------NFDHKNETLSITVQPGEGNKAELSDMRSLSGGERS 1025

  Fly  1213 LSSLALVFALHYYKPSPLYFMDEIDAALDFKNVSI---VGHYIKERTKNAQFIIVSLRVNMFEL- 1273
            .|::..:.:|.....||...:||.|..:|..|..|   :...:.:..:..|||:::.: ||..|
 Frog  1026 FSNVCFILSLWSIAESPFRCLDEFDVYMDMVNRRISMDMMLKVADSQRFRQFILLTPQ-NMSSLP 1089

  Fly  1274 ANFLVGIYKVSDCTDSITMLNYPP 1297
            ::.::.|.::.|.....|.|.:.|
 Frog  1090 SSSIIRILRMKDPERGQTTLPFQP 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
glu	NP_723996.1	ABC_SMC4_euk	87..>246	CDD:213241	38/169 (22%)
		Smc	89..1281	CDD:224117	244/1272 (19%)
		SMC_hinge	618..733	CDD:214944	26/136 (19%)
		ATP-synt_B	<825..904	CDD:304375	11/78 (14%)
		ABC_SMC4_euk	<1196..1290	CDD:213241	24/100 (24%)
smc6	XP_031758814.1	Smc	81..1101	CDD:224117	245/1276 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910