Protein Alignment glu and smc4

DIOPT Version :9

• Sequence 1: NP_723996.1
• Gene: glu / 35001
• FlyBaseID: FBgn0015391
• Length: 1409
• Species: Drosophila melanogaster
• Sequence 2: XP_002933283.1
• Gene: smc4 / 100145810
• XenbaseID: XB-GENE-5865855
• Length: 1286
• Species: Xenopus tropicalis
• Alignment Length: 1286
• Identity: 525/1286 - (40%)
• Similarity: 794/1286 - (61%)
• Gaps: 61/1286 - (4%)

  Fly    19 QSGQFRVPQLTAQQQLRAQQQQEEEDAAVD--ALDDALIFDDEEGGTRIGDIYIPPPVPPHCSME 81
            |:||...|            .||..:..||  :|::.|             ..||||.||..:.|
 Frog    27 QAGQAEAP------------TQESHNEVVDNRSLEEIL-------------SSIPPPPPPAMTNE 66

  Fly    82 STGPRLIISKIVNRNFKSYAGEVELGPFHQSFTAIIGPNGSGKSNVIDSMMFVFGCRANRIRCKR 146
            :..|||:|:.|||:||||||||..|||||:.|:.||||||||||||||||:||||.||.:||.|:
 Frog    67 AGAPRLMITHIVNQNFKSYAGERILGPFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKK 131

  Fly   147 VSTLIHSSSSYPNLRSCSVAVHFKQIVDKGDGTCEDVPDSSIVIERTAMSDNSSYYQINDKRAQL 211
            :|.|||:|..:.:::||:|.|||::|.||.....|.:|:|:..:.|||..||||.|.|:.|:|..
 Frog   132 LSVLIHNSDEHKDVQSCTVEVHFQKITDKEGDDFEVIPNSNFYVSRTAYKDNSSVYHISGKKATF 196

  Fly   212 KDVAKLLKKHHVDLEHNRFLILQGEVESIAMMKPKGQTENETGMLEYLEDIVGTQRYIRPLQQIN 276
            |||..||:.|.:||:||||||||||||.|||||||||||::.|||||||||:|:||...|:|.:.
 Frog   197 KDVGLLLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGSQRLKEPIQILC 261

  Fly   277 QRVDQLTDDRTEKHNRCKLAEREMKDLEQPFNEAVDYLKKENELVRTKSFHIQKIISIKKSKLEQ 341
            :||:.|.:.|.||.||.|:.|:|...||...|:|:::|..|||..:.|:...|..|...:.:...
 Frog   262 RRVELLNEQRGEKLNRVKMVEKEKDALEGEKNKAIEFLTVENETFKKKNQLCQYYIHDLQKRSRD 326

  Fly   342 YTQEHEACAEELKTHDEGTAALKQSRAEKETIIRKEIEEYEALVKKREQIKKRLVTVESAYTEIQ 406
            ...:.|...|:.|...|.:..|.::..||...::...::...:.|..|:.:::...::....:.:
 Frog   327 MEAQKEKIQEDTKEISEKSNTLLETMKEKNKGLKDVEKQLNKITKFIEENREKFTQLDLQDVDTR 391

  Fly   407 STMENTNKQRKKDKAQIEKNEKELEDLHKLPEKNQREI-EDCNKKLESLEVSKVTLNEELEKQQA 470
            ..::::..:.||.:.|::|:::::|::..:|..:|:.| |:.||| :.||..|....|:|:....
 Frog   392 EKLKHSKSKVKKLQKQLQKDKEKVEEIKNVPANSQKIITEETNKK-DLLEKQKEKEEEKLKDVMD 455

  Fly   471 ELTKTTAPLTEKRLKLSDELVGLKEKVNTAKGEVQVFESQLKILKQAETTESRKYETLKSSYEQS 535
            .|.|.|..|.|::.....||:.:.:.||.|:.::.|.:|:|.|......|...:....|.:...:
 Frog   456 SLKKETQGLQEEKEVKEKELMEISKTVNEARSKMDVAQSELDIYLSRHNTALSQLNKAKEALNTA 520

  Fly   536 QKSLEEKVTRVDELKESIPRMKTEIASKSAEVDKMVKEERNLSMQCNKLRTEINERSSVMQAQRS 600
            ..:|:|:...:.||:..:|:.:.::..:..|::.:|.||.|:..:..:||.::.|..|.:.|.||
 Frog   521 SATLKERRAAIKELETKLPKDEVDLKKQEKELESLVSEEANIKNEVRELRHKVEEARSSLSANRS 585

  Fly   601 NNKVLDFLMRMKMEGKIPGILGRLGDLGGIDAKYDIAISTACGRLDNIVTDNYETASAAIGALKE 665
            ..||||.|::.|..||||||.|||||||.||.|||:|||::||.||:||.|..:||...:..||:
 Frog   586 RGKVLDALIQQKKSGKIPGIFGRLGDLGAIDEKYDVAISSSCGALDHIVVDTIDTAQECVNFLKK 650

  Fly   666 YNVGRATFITLDKIEHHRREANSRINTPENVPRLYDLVKVEDDRVRTAFYFALRNTLVCDDLEQG 730
            .|||.||||.|||::...:..: :|.||||:|||:|:|||:|:::|.|||||||:|||.::|:|.
 Frog   651 QNVGVATFIGLDKMKVWEKGLD-KIQTPENIPRLFDMVKVKDEKIRPAFYFALRDTLVANNLDQA 714

  Fly   731 TRIAYGRE-RYRVVTLRGEMIEMTGTMSGGGSRPIRGKMGTQVRTKTAESADSSQISQKALEDMQ 794
            |::|:.:: |:|||||:|::||.:|||:|||.:.::|:||:.|..:.::.  ..||.:..|:...
 Frog   715 TKVAFQKDKRWRVVTLQGQIIEQSGTMTGGGGKVMKGRMGSSVMVEISDG--QLQIMENKLKTDT 777

  Fly   795 IQAEELQARVNYCQEQQGSLEREIQTLKNGLQRDEAEYKRLAVSITSLEQQ---MASNLKQCEAQ 856
            .:|..:|.|..:.:|....|.:..:.:||       .:::...|:.||.:|   :.:.:|:.|.
 Frog   778 DKATAIQDRKAHLEEGVAKLRQATREMKN-------TFEKYTASLQSLSEQEVHLKAQVKELEV- 834

  Fly   857 RQRMLKKTTDERAVKEREEQIEAAKQELEQAQFAEQA--VSSQIEEIQNQYDTLRNESVKPVEAK 919
              .:.....|:...|:.|:.:||.|:|.|..  ||:|  |.::::.:......:.|..:|..:.|
 Frog   835 --NVAAAAPDKAQQKQMEKNLEALKKEYETV--AEKAGKVEAEVKRLHKLIVDINNHKLKAQQDK 895

  Fly   920 IKKVNSQIEKLAANVRSLNVGLATADRNITK----ITGNNNNLRENIKAAEEKLKSLNEDRNKAK 980
            :.|||.:|::.|:.:....|.:.|||||:.|    :......:.||.|..||    |.||..:.:
 Frog   896 LDKVNKEIDECASAITKAQVSIKTADRNLKKSEEAVARTEKEIVENDKTIEE----LTEDLKQLE 956

  Fly   981 EKKEELEKEIEESEASIEGAKSQSSDIKKEIDEITKEENKRNIERIEIDTKLQAAAGKMNKVKND 1045
            ||...:..|.:|:|.|:...:.|..::.:||..|.::|:....|.:.|...::.....:.:.::.
 Frog   957 EKATAVMNECKEAEGSLPEVQEQHRNLLQEIKAIQEKEHALQKEALNIRLNIEQIESHIAEHQSK 1021

  Fly  1046 IPGWQAQLAPLKLNEIPGETEPQAPLKELNEEELEA-ETLEALQYKQTMLEEDLKTKKPNLSCIK 1109
            |..||.::..:.|:.|  |..|:..|..|.:||||| :..:.:..:..:||......||||..|.
 Frog  1022 IKYWQKEITKISLHRI--EDNPEEVLAVLAQEELEAIKDPDQIINQIALLEAKSHEMKPNLGAIA 1084

  Fly  1110 EFNEKRLVYLDRVRVLEDITSKRNEMRDKYEEVRKRRYKEFMDGFSIITRKLKEMYQMITLGGDA 1174
            |:.:|..:||.||..|::||::|:..|..||::||:|..|||.||:|||.||||.|||:||||||
 Frog  1085 EYKKKEELYLQRVAELDEITNERDNFRRAYEDLRKQRLNEFMAGFNIITNKLKENYQMLTLGGDA 1149

  Fly  1175 ELELVDSMDPFTEGVNFTVRPPKKSWKYISNLSGGEKTLSSLALVFALHYYKPSPLYFMDEIDAA 1239
            |||||||:|||:||:.|:|||||||||.|.|||||||||||||||||||:|||:|||||||||||
 Frog  1150 ELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAA 1214

  Fly  1240 LDFKNVSIVGHYIKERTKNAQFIIVSLRVNMFELANFLVGIYKVSDCTDSI 1290
            |||||||||..||.|:||||||||:|||.||||:|:.|:||||..:.|.|:
 Frog  1215 LDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEIADRLIGIYKTHNTTKSV 1265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
glu	NP_723996.1	ABC_SMC4_euk	87..>246	CDD:213241	97/158 (61%)
		Smc	89..1281	CDD:224117	500/1203 (42%)
		SMC_hinge	618..733	CDD:214944	66/114 (58%)
		ATP-synt_B	<825..904	CDD:304375	18/83 (22%)
		ABC_SMC4_euk	<1196..1290	CDD:213241	74/93 (80%)
smc4	XP_002933283.1	SMC_N	73..1264	CDD:308206	504/1212 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	882	1.000	Domainoid score	I57
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4015
Inparanoid	1	1.050	911	1.000	Inparanoid score	I363
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326079at2759
OrthoFinder	1	1.000	-	-		FOG0003579
OrthoInspector	1	1.000	-	-		oto105165
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1354
SonicParanoid	1	1.000	-	-		X3446
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090