DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17904 and NBP35

DIOPT Version :9

Sequence 1:	NP_609805.1	Gene:	CG17904 / 35000	FlyBaseID:	FBgn0032597	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_011424.3	Gene:	NBP35 / 852789	SGDID:	S000003059	Length:	328	Species:	Saccharomyces cerevisiae

Alignment Length:	290	Identity:	148/290 - (51%)
Similarity:	205/290 - (70%)	Gaps:	5/290 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAPPPEHCPGVESEEAGKGSACSGCPNQGLCSDPNKKLEDPGKALVVESMKDVKHKLLILSGKG 65
            :..|.||||||.||:.|||..||.||.|:.:| :...|..||...|:.:::..::||:|:|||||
Yeast    19 LNQPEPEHCPGPESDMAGKSDACGGCANKEIC-ESLPKGPDPDIPLITDNLSGIEHKILVLSGKG 82

  Fly    66 GVGKSTVTSLLTRYLARSNPDSNFGVLDIDICGPSQPRLMGALGESVHQSGYGWSPVGIEDNVCL 130
            ||||||..::|:..|: ::.|...|.:|:||||||.|.::|.:.|:||:|..||:||.:.||:..
Yeast    83 GVGKSTFAAMLSWALS-ADEDLQVGAMDLDICGPSLPHMLGCIKETVHESNSGWTPVYVTDNLAT 146

  Fly   131 MSIGFLLGSVDDAIIWRGPKKNGMIRQFLSEVDWGNLDLLLLDTPPGTSDEHLSVVSYLKDDANP 195
            |||.::|...|.||||||.|||.:|::||.:|||..||.|::||||||||||:|:..|:::....
Yeast   147 MSIQYMLPEDDSAIIWRGSKKNLLIKKFLKDVDWDKLDYLVIDTPPGTSDEHISINKYMRESGID 211

  Fly   196 ESLRAVMVTTPQEVSLLDVRKEINFCKKQNIPIVGVIENMSSFRCGHCGNSSEIFPAKTGGAAAM 260
               .|::|||||||:||||||||:||||..|.|:|::||||.|.|.:|...|:||.|.|||..|:
Yeast   212 ---GALVVTTPQEVALLDVRKEIDFCKKAGINILGLVENMSGFVCPNCKGESQIFKATTGGGEAL 273

  Fly   261 CAEMGIPLLGSLPLDQQISKACDSGEDLTE 290
            |.|:||..|||:|||.:|.|:||.||...:
Yeast   274 CKELGIKFLGSVPLDPRIGKSCDMGESFLD 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17904	NP_609805.1	Mrp	10..282	CDD:223563	139/271 (51%)
CG17904	NP_609805.1	ParA	54..307	CDD:287566	126/237 (53%)
NBP35	NP_011424.3	ParA	70..321	CDD:402307	126/238 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344610
Domainoid	1	1.000	267	1.000	Domainoid score	I286
eggNOG	1	0.900	-	-		E1_COG0489
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1857
Inparanoid	1	1.050	312	1.000	Inparanoid score	I470
Isobase	1	0.950	-	0	Normalized mean entropy	S354
OMA	1	1.010	-	-		QHG53899
OrthoFinder	1	1.000	-	-		FOG0001227
OrthoInspector	1	1.000	-	-		oto99827
orthoMCL	1	0.900	-	-		OOG6_100169
Panther	1	1.100	-	-	LDO	PTHR23264
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R796
SonicParanoid	1	1.000	-	-		X3047
TreeFam	1	0.960	-	-
	16	15.740