Protein Alignment APOH and hig

DIOPT Version :9

• Sequence 1: NP_000033.2
• Gene: APOH / 350
• HGNCID: 616
• Length: 345
• Species: Homo sapiens
• Sequence 2: NP_724773.1
• Gene: hig / 35949
• FlyBaseID: FBgn0010114
• Length: 958
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 79/270 - (29%)
• Similarity: 105/270 - (38%)
• Gaps: 45/270 - (16%)

Human    16 VAIAGRTCPKPDDLPFSTVVPLKTFYEP---GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTL 77
            |.:|..|||:..:    .:.|||...|.   |:...|.|..|:...|.... .|..:|.|...|.
  Fly   707 VVVATSTCPQLTE----PLAPLKLRLEGNKLGQRAHYECPEGFRLDGAWNA-TCLASGNWSSPTP 766

Human    78 KCTPRVCPFAGILENGAVRYTTFEYPNTIS-----FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
            .|....||   .||......:..|. ||.:     |.|..||.|.|.....|...|.||..:|.|
  Fly   767 TCHAIQCP---RLELDDPHLSLIEL-NTSAWGRAVFKCQWGFKLTGPAQLDCEPSGVWSGPVPRC 827

Human   138 APIICPPPSIPTFATLRVYKPSAGNNSLYR------DTAVFECLPQHAMFGNDTITCTTHGNWTK 196
            ..|.|..|..|....:       |..||.:      ....|.|...|::.|..:|.||.:|.|:.
  Fly   828 KVIQCVMPVAPLNGRI-------GGTSLSQRRLTVGALVTFSCNDGHSLVGESSIICTENGQWSH 885

Human   197 LPECREVKCPFPSRPDNGFV-----NYPAKPTLYYKDKATFGCHDGY--SLDG-PEEIECTKLGN 253
            .|...:.:||:|..|.||.:     ||.|      .|..:..|..|:  |.:| ||..:|...|.
  Fly   886 SPPFCKSQCPYPGDPPNGLIAPLKFNYDA------GDYLSVQCRPGFVQSYEGPPERPKCQPDGR 944

Human   254 WSA-MPSCKA 262
            ||. ||.||:
  Fly   945 WSGPMPKCKS 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APOH	NP_000033.2	CCP	41..260	CDD:332582	69/241 (29%)
		Sushi_2	261..345	CDD:312533	1/2 (50%)
		Sushi-like	263..345		79/270 (29%)
hig	NP_724773.1	PHA02927	705..952	CDD:222943	77/266 (29%)
		CCP	714..768	CDD:153056	15/58 (26%)
		CCP	<795..828	CDD:153056	11/32 (34%)
		CCP	832..891	CDD:153056	16/65 (25%)
		Sushi	894..952	CDD:278512	22/63 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7190
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19325
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.050