DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ACADS and CG3902

DIOPT Version :9

Sequence 1:	NP_000008.1	Gene:	ACADS / 35	HGNCID:	90	Length:	412	Species:	Homo sapiens
Sequence 2:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster

Alignment Length:	403	Identity:	147/403 - (36%)
Similarity:	240/403 - (59%)	Gaps:	8/403 - (1%)

- Green bases have known domain annotations that are detailed below.

Human    15 RALCPRAWRQLHTIYQSVELP-------ETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVK 72
            |.|...|.:|...:..:..||       :..:|:.:|....|::::.|:..::|.||.|..:.||
  Fly    11 RMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVKKMDFEHKFDPSVVK 75

Human    73 KMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQ 137
            .:...||:.:::..||||:|.:::...:.:||:|:...:....:.::|:|....::|||:.|||.
  Fly    76 AVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKA 140

Human   138 AWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTD 202
            .:: |..:.:..|.|||:|||.||||.:..|.|:.:|..:|:||:|.||:|:..|...::||:..
  Fly   141 KYL-PKLAQEYAGSFALTEPGAGSDAFSLKTVAKKDGSHYVINGSKMWISNSDVAGVFLIFANAK 204

Human   203 RALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQT 267
            .....:||:.|:|...||||.:.|.|||||||.|.|..|.|::.|:|:::|||..|.|:|.|...
  Fly   205 PEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYAAGF 269

Human   268 LDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAA 332
            |:.||||||:|.:|:||...|..:.|...|..||..:...|.:|.::|.:|..:|:|||:|:.||
  Fly   270 LNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAA 334

Human   333 MLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEI 397
            .|::...||.|||||||..|||.|...:.:.:..:||:|:..:.|.|::|||.:|..|||||:.:
  Fly   335 RLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNM 399

Human   398 QRLVIAGHLLRSY 410
            |...||..:.:.|
  Fly   400 QLSTIAKCIKKDY 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACADS	NP_000008.1	CaiA	33..412	CDD:224871	143/385 (37%)
ACADS	NP_000008.1	SCAD_SBCAD	36..408	CDD:173847	140/371 (38%)
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	141/377 (37%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	140/371 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820