DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta4 and PUP1

DIOPT Version :9

Sequence 1:	NP_001260511.1	Gene:	Prosbeta4 / 34999	FlyBaseID:	FBgn0032596	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_014800.3	Gene:	PUP1 / 854328	SGDID:	S000005683	Length:	261	Species:	Saccharomyces cerevisiae

Alignment Length:	188	Identity:	46/188 - (24%)
Similarity:	84/188 - (44%)	Gaps:	28/188 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TLLGIKGPDFVMLAADTTHARSIIVMKEDQNKIHKVSDSLLISTVGESGDTEQFTEFISKNIALY 67
            |::|:|..:.|::||||...:..||..::..|:|::|..:..:..|.:.|||..|:.|..||.|:
Yeast    31 TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELH 95

  Fly    68 KMRNGYDLSPRESAHFTRKNLAEYLRSRTPYQVFMFVAGYDPNAGPELTFIDYLANALPVNYAGH 132
            .:....:.....:....:::|.:|   :.....::.|||.|| .|..|..|....:.....|...
Yeast    96 SLYTSREPRVVSALQMLKQHLFKY---QGHIGAYLIVAGVDP-TGSHLFSIHAHGSTDVGYYLSL 156

  Fly   133 GYGAIFASSIYDRYWHPNITQAEA---------------------YDVFKKCIAEIQK 169
            |.|::.|.::.:.:|..::|:.||                     .||   |:.||.|
Yeast   157 GSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV---CVMEIGK 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta4	NP_001260511.1	PRE1	1..194	CDD:223711	46/188 (24%)
Prosbeta4	NP_001260511.1	proteasome_beta_type_2	1..192	CDD:239727	46/188 (24%)
PUP1	NP_014800.3	proteasome_beta_type_7	30..219	CDD:239732	46/188 (24%)
PUP1	NP_014800.3	Pr_beta_C	223..257	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810