Protein Alignment Prosbeta4 and PSMB5

DIOPT Version :10

• Sequence 1: NP_609804.1
• Gene: Prosbeta4 / 34999
• FlyBaseID: FBgn0032596
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_002788.1
• Gene: PSMB5 / 5693
• HGNCID: 9542
• Length: 263
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 47/204 - (23%)
• Similarity: 85/204 - (41%)
• Gaps: 25/204 - (12%)

  Fly     3 TLLGIKGPDFVMLAADTTHARSIIVMKEDQNKIHKVSDSLLISTVGESGDTEQFTEFISKNIALY 67
            |.|..|....|::|||:.......:..:...|:.:::..||.:..|.:.|...:...:::...:|
Human    61 TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIY 125

  Fly    68 KMRNGYDLSPRESAHFTRKNLAEYLRSRTPYQ-------VFMFVAGYDPNAGPELTFIDYLANAL 125
            ::||    ..|.|.....|.||..:     ||       :...:.|:| ..||.|.::|...|.:
Human   126 ELRN----KERISVAAASKLLANMV-----YQYKGMGLSMGTMICGWD-KRGPGLYYVDSEGNRI 180

  Fly   126 PVNYAGHGYGAIFASSIYDRYWHPNITQAEAYDVFKKCIAEIQKR-----LVVNLKNFTV---AV 182
            .......|.|:::|..:.||.:..::...:|||:.::.|.:...|     ..|||.:...   ..
Human   181 SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIR 245

  Fly   183 VDKDGVRDL 191
            |..|.|.||
Human   246 VSSDNVADL 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta4	NP_609804.1	proteasome_beta_type_2	1..192	CDD:239727	47/204 (23%)
PSMB5	NP_002788.1	proteasome_beta_type_5	60..247	CDD:239730	42/195 (22%)