Protein Alignment VhaSFD and VMA13

DIOPT Version :9

• Sequence 1: NP_723992.1
• Gene: VhaSFD / 34997
• FlyBaseID: FBgn0027779
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_015361.1
• Gene: VMA13 / 856148
• SGDID: S000006240
• Length: 478
• Species: Saccharomyces cerevisiae
• Alignment Length: 567
• Identity: 146/567 - (25%)
• Similarity: 231/567 - (40%)
• Gaps: 152/567 - (26%)

  Fly    15 IAATSVLQQQA------ADIRTRTINWASYMQSQMISEEDYKAISAL----------DKSRASFL 63
            :.||.:|....      :.||:|::.|.:..:|:.:||.|.....||          |...:|..
Yeast     1 MGATKILMDSTHFNEIRSIIRSRSVAWDALARSEELSEIDASTAKALESILVKKNIGDGLSSSNN 65

  Fly    64 AQNSSQV-VKTLLNLVSHLS-------KDSTIQYILVLL------DD---LLQEDRSRVDLFHDT 111
            |.:..:| .|||:.|:..||       |.|....|..||      ||   ..|||..:::...|.
Yeast    66 AHSGFKVNGKTLIPLIHLLSTSDNEDCKKSVQNLIAELLSSDKYGDDTVKFFQEDPKQLEQLFDV 130

  Fly   112 AGKLKQCIWGPFLNLLNRQDGFIVNMSSRILAKFACWGHETMPKSDLNFYLQFLKDQLASNGLAY 176
            :.|      |.|..:|  ..||  |:.| :|.:......:.:.|...|..|..:...:......|
Yeast   131 SLK------GDFQTVL--ISGF--NVVS-LLVQNGLHNVKLVEKLLKNNNLINILQNIEQMDTCY 184

  Fly   177 -----LQEMAQLAKRTQTILVHTHGKDKDHHGHQYSPTLAQLQQQHELAERANESYREVGVGSDH 236
                 |||:|.:.:....|.:|.         .::.|||.::.|      ||.:|
Yeast   185 VCIRLLQELAVIPEYRDVIWLHE---------KKFMPTLFKILQ------RATDS---------- 224

  Fly   237 QQQDGKCVIPNNEYIQSVARCLQMMLRVDEYRFAFVGVDGISTLIRILSTRVNFQVQYQLIFCLW 301
                                  |:..|:                :...|..:..|:||..:..:|
Yeast   225 ----------------------QLATRI----------------VATNSNHLGIQLQYHSLLLIW 251

  Fly   302 VLTFNPLLAAKMNKFSVIPILADIL------SDCAKEKVTRIILAVFRNLIEKPEDSSVAKDHCI 360
            :|||||:.|.::    |...|:|.|      ....||||:|:.:::.....     |:..|.|
Yeast   252 LLTFNPVFANEL----VQKYLSDFLDLLKLVKITIKEKVSRLCISIILQCC-----STRVKQH-- 305

  Fly   361 AMVQCKVLKQLSI----------LEQRRFDDEDITADVEYLSEKLQNSVQDLSSFDEYATEVRSG 415
                .||:|||.:          |.:|::.||::..|:..|.|.|:|..|:|:|||||..|:.|.
Yeast   306 ----KKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSK 366

  Fly   416 RLEWSPVHKSAKFWRENAQRLNEKNYELLRILVHLLE---------TSKDAIILSVACFDIGEYV 471
            .|.|||.|....||.:|.....:.||::.|.|:.||:         ..::.||:.||..||...|
Yeast   367 LLCWSPPHVDNGFWSDNIDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVV 431

  Fly   472 RHYPRGKHVLEQLGGKQIVMQHLGHEDPNVRYEALLAVQKLMVHNWE 518
            ...|....||::.|||..:|:.|.|.|..|:||||.|.|.::.:.::
Yeast   432 ELLPESIDVLDKTGGKADIMELLNHSDSRVKYEALKATQAIIGYTFK 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VhaSFD	NP_723992.1	VATPase_H	19..518	CDD:238159	144/561 (26%)
VMA13	NP_015361.1	VMA13	1..478	CDD:227556	146/565 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343030
Domainoid	1	1.000	84	1.000	Domainoid score	I1922
eggNOG	1	0.900	-	-		E1_COG5231
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I1224
Isobase	1	0.950	-	0	Normalized mean entropy	S1675
OMA	1	1.010	-	-		QHG54625
OrthoFinder	1	1.000	-	-		FOG0004292
OrthoInspector	1	1.000	-	-		oto100308
orthoMCL	1	0.900	-	-		OOG6_101800
Panther	1	1.100	-	-	LDO	PTHR10698
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1635
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.780