Protein Alignment VhaSFD and atp6v1h

DIOPT Version :10

• Sequence 1: NP_723992.1
• Gene: VhaSFD / 34997
• FlyBaseID: FBgn0027779
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001278637.1
• Gene: atp6v1h / 286779
• ZFINID: ZDB-GENE-021219-2
• Length: 481
• Species: Danio rerio
• Alignment Length: 529
• Identity: 258/529 - (48%)
• Similarity: 347/529 - (65%)
• Gaps: 60/529 - (11%)

  Fly    12 IDMIAATSVLQQQAADIRTRTINWASYMQSQMISEEDYKAISALD----KSRASFLAQNSSQVVK 72
            :|....|:::..:||::|...:||.||:|.||||.||.:.|...:    :.:.:.|.....|..|
Zfish     7 VDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISGEDCEFIKKFEVAGSEDKQAILTNEGHQCAK 71

  Fly    73 TLLNLVSHLSKDSTIQYILVLLDDLLQEDRSRVDLFHDTAGKLKQCIWGPFLNLLNRQDGFIVNM 137
            |.|||::|:||:.|:||||.|:||.|||:..||::|.|.|.|.|...|..||.:|||||.|.|:|
Zfish    72 TFLNLMAHISKEQTVQYILTLIDDTLQENHQRVNIFFDYAKKTKNTAWSYFLPMLNRQDLFTVHM 136

  Fly   138 SSRILAKFACWGHETMPKSDLNFYLQFLKDQLASNGLAYLQEMAQLAKRTQTILVHTHGKDKDHH 202
            ::||:||.|.||.:.|..||||:|..::|.||:|..|                           |
Zfish   137 AARIIAKLAAWGRDLMEGSDLNYYFNWIKTQLSSQKL---------------------------H 174

  Fly   203 GHQYSPTLAQLQQQHELAERANESYREVGVGSDHQQQDGKCVIPNNEYIQSVARCLQMMLRVDEY 267
            |....|                      |.|:....:       :::|:|.||.|||:||||:||
Zfish   175 GTGAEP----------------------GTGTISPSE-------SSQYVQCVAGCLQLMLRVNEY 210

  Fly   268 RFAFVGVDGISTLIRILSTRVNFQVQYQLIFCLWVLTFNPLLAAKMNKFSVIPILADILSDCAKE 332
            |||:|..||::.:..:||.:..||:|||:|||:|:|.|:|.|..::.:::|:|.|:|||.:..||
Zfish   211 RFAWVEADGVNCITAVLSNKCGFQLQYQMIFCVWLLAFSPQLCEQLRRYNVVPALSDILQESVKE 275

  Fly   333 KVTRIILAVFRNLIEKPEDSSVAKDHCIAMVQCKVLKQLSILEQRRFDDEDITADVEYLSEKLQN 397
            ||||||||.||||:||..:....:::.:||:||||||||..|:|:::||||||.|:::|.|:|..
Zfish   276 KVTRIILAAFRNLLEKSAERETRQEYALAMIQCKVLKQLENLDQQKYDDEDITDDIKFLLERLGE 340

  Fly   398 SVQDLSSFDEYATEVRSGRLEWSPVHKSAKFWRENAQRLNEKNYELLRILVHLLETSKDAIILSV 462
            |||||||||||::|::||||||||||||.|||||||.||||||||||:||..|||.|.|..:::|
Zfish   341 SVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTRLLEVSDDPQVIAV 405

  Fly   463 ACFDIGEYVRHYPRGKHVLEQLGGKQIVMQHLGHEDPNVRYEALLAVQKLMVHNWEYLGKQLEKE 527
            |..|:|||||||||||.|:|||||||:||.|:.|||..|||.||||||||||||||||||||:..
Zfish   406 AAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQLVRYNALLAVQKLMVHNWEYLGKQLQST 470

  Fly   528 NENQKQGAA 536
            .:.....||
Zfish   471 EQTTPAVAA 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VhaSFD	NP_723992.1	VATPase_H	19..518	CDD:238159	246/502 (49%)
atp6v1h	NP_001278637.1	VATPase_H	14..461	CDD:238159	246/502 (49%)