Protein Alignment VhaSFD and vha-15

DIOPT Version :10

• Sequence 1: NP_723992.1
• Gene: VhaSFD / 34997
• FlyBaseID: FBgn0027779
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_508412.1
• Gene: vha-15 / 180534
• WormBaseID: WBGene00020507
• Length: 470
• Species: Caenorhabditis elegans
• Alignment Length: 531
• Identity: 245/531 - (46%)
• Similarity: 325/531 - (61%)
• Gaps: 83/531 - (15%)

  Fly     7 LPEENI---DMIAATSVLQQQAADIRTRTINWASYMQSQMISEEDYKAISALD-----KSRASFL 63
            :|..||   ||:.|||.||.:|.::|....||.||.:||||.|:||..|::.:     :.|...|
 Worm     4 VPHHNIPAVDMLNATSRLQLEAQELRNNKPNWGSYFRSQMIQEDDYNFITSFENAKSKEERDQVL 68

  Fly    64 AQNSS--QVVKTLLNLVSHLSKDSTIQYILVLLDDLLQEDRSRVDLFHDTAGKLKQCIWGPFLNL 126
            |.|::  |..||:.||::.::||..::|:|.|.||:||||:|||:|||..|.:.|:.:|..:|.:
 Worm    69 AANNANGQAAKTMANLITQVAKDQNVRYVLTLFDDMLQEDKSRVELFHSAAARQKRTVWSQYLGI 133

  Fly   127 LNRQDGFIVNMSSRILAKFACWGHETMPKSDLNFYLQFLKDQLASNGLAYLQEMAQLAKRTQTIL 191
            |.|||.||||..|.|:||.||:|...|...||.:|..|||:||               |.:.|
 Worm   134 LQRQDNFIVNQMSSIIAKLACFGTTRMEGQDLQYYFSFLKEQL---------------KNSTT-- 181

  Fly   192 VHTHGKDKDHHGHQYSPTLAQLQQQHELAERANESYREVGVGSDHQQQDGKCVIPNNEYIQSVAR 256
                                                                    |:|:.:.||
 Worm   182 --------------------------------------------------------NDYMNTTAR 190

  Fly   257 CLQMMLRVDEYRFAFVGVDGISTLIRILSTRVNFQVQYQLIFCLWVLTFNPLLAAKMNKFSVIPI 321
            |||||||.||||..||..||:.||:..|:.:.|||:||||||.:|.||||..:|.|.....:|..
 Worm   191 CLQMMLRHDEYRHEFVDSDGVQTLVTALNGKTNFQLQYQLIFAVWCLTFNADIARKAPSLGLIQA 255

  Fly   322 LADILSDCAKEKVTRIILAVFRNLIEKPEDSSVAKDHCIAMVQCKVLKQLSILEQRRFDDEDITA 386
            |.||||:..||||.|||||.|.|::.|.::..|.::..:.|||||.||.|.:::.:::||.|:..
 Worm   256 LGDILSESTKEKVIRIILASFVNILSKVDEREVKREAALQMVQCKTLKTLELMDAKKYDDPDLED 320

  Fly   387 DVEYLSEKLQNSVQDLSSFDEYATEVRSGRLEWSPVHKSAKFWRENAQRLNEKNYELLRILVHLL 451
            ||::|:|:|..||.||||:|||.:|||||||:|||||||.|||||||.:.|:|.:|:::||:.||
 Worm   321 DVKFLTEELTLSVHDLSSYDEYYSEVRSGRLQWSPVHKSEKFWRENASKFNDKQFEVVKILIKLL 385

  Fly   452 ETSKDAIILSVACFDIGEYVRHYPRGKHVLEQLGGKQIVMQHLGHEDPNVRYEALLAVQKLMVHN 516
            |:|.|.:||.||..|||||||||||||.|:||..||..||:.|..|||||||.||||||||||||
 Worm   386 ESSHDPLILCVASHDIGEYVRHYPRGKTVVEQYQGKAAVMRLLTAEDPNVRYHALLAVQKLMVHN 450

  Fly   517 WEYLGKQLEKE 527
            ||||||||:.:
 Worm   451 WEYLGKQLDSD 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VhaSFD	NP_723992.1	VATPase_H	19..518	CDD:238159	230/505 (46%)
vha-15	NP_508412.1	VATPase_H	19..452	CDD:238159	230/505 (46%)