Protein Alignment VhaSFD and vha-18

DIOPT Version :9

• Sequence 1: NP_723992.1
• Gene: VhaSFD / 34997
• FlyBaseID: FBgn0027779
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_505171.1
• Gene: vha-18 / 179223
• WormBaseID: WBGene00018698
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 189/522 - (36%)
• Similarity: 287/522 - (54%)
• Gaps: 82/522 - (15%)

  Fly    10 ENIDMIAATSVLQQQAADIRTRTINWASYMQSQMISEEDYKAISALDKS-----RASFLAQNSSQ 69
            ||.|:|  .:..|::|..:|....||..:.:::||::.||..|....::     |::.|:....:
 Worm     5 ENQDLI--RTHFQKEADKVRAMKTNWGLFTRTRMIAQSDYDFIVTYQQAENEAERSTVLSVFKEK 67

  Fly    70 VVKTLLNLVSHLSKDSTIQYILVLLDDLLQEDRSRVDLFHDTAGKLKQCIWGPFLNLLNRQDGFI 134
            .|...::|:|.:|||..::|.|.|:||:|:||.:|..:|.|.|..||:..:..|:.||:|||.:|
 Worm    68 AVYAFVHLMSQISKDDYVRYTLTLIDDMLREDVTRTIIFEDVAVLLKRSPFSFFMGLLHRQDQYI 132

  Fly   135 VNMSSRILAKFACWGHETMPKSDLNFYLQFLKDQLASNGLAYLQEMAQLAKRTQTILVHTHGKDK 199
            |:::..||.|.|.:|:..:...:|::.:..||:.:
 Worm   133 VHITFSILTKMAVFGNIKLSGDELDYCMGSLKEAM------------------------------ 167

  Fly   200 DHHGHQYSPTLAQLQQQHELAERANESYREVGVGSDHQQQDGKCVIPNNEYIQSVARCLQMMLRV 264
             :.|                                          .||:||.:..||:|.:.|.
 Worm   168 -NRG------------------------------------------TNNDYIVTAVRCMQTLFRF 189

  Fly   265 DEYRFAFVGVDGISTLIRIL-STR-VNFQVQYQLIFCLWVLTFNPLLAAKMNKFSVIPILADILS 327
            |.||.:||.::|..:|...| ||| ..||:|||:|||:|:||||...|......::|..::.||.
 Worm   190 DPYRVSFVNINGYDSLTHALYSTRKCGFQIQYQIIFCMWLLTFNGHAAEVALSGNLIQTISGILG 254

  Fly   328 DCAKEKVTRIILAVFRNLIEKPEDSSVAKDHCIAMVQCKVLKQLSILEQRRFDDEDITADVEYLS 392
            :|.||||.||:::..||||...:|..:.|...:.|:|.::..:|..||.|:|.|.|:..|:.||.
 Worm   255 NCQKEKVIRIVVSTLRNLITSNQDVYMKKQAALQMIQNRIPTKLDHLENRKFTDVDLVEDMVYLQ 319

  Fly   393 EKLQNSVQDLSSFDEYATEVRSGRLEWSPVHKSAKFWRENAQRLNEKNYELLRILVHLLETSKDA 457
            .:|:..||.|:|||||..|:|.|.|.|||.||...||.|||.|||:...|||::||.:||.|.|.
 Worm   320 TELKKVVQVLTSFDEYENELRQGSLHWSPAHKCEVFWNENAHRLNDNRQELLKLLVAMLEKSNDP 384

  Fly   458 IILSVACFDIGEYVRHYPRGKHVLEQLGGKQIVMQHLGHEDPNVRYEALLAVQKLMVHNWEYLGK 522
            ::|.||..||||:||:|||||..:||||||:.:|:.|..:||||||.||||.||||::||:.||.
 Worm   385 LVLCVAAHDIGEFVRYYPRGKLKVEQLGGKEAMMRLLTVKDPNVRYHALLAAQKLMINNWKDLGL 449

  Fly   523 QL 524
            ::
 Worm   450 EI 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VhaSFD	NP_723992.1	VATPase_H	19..518	CDD:238159	182/505 (36%)
vha-18	NP_505171.1	VATPase_H	12..445	CDD:238159	182/505 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158280
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5231
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1675
OMA	1	1.010	-	-		QHG54625
OrthoDB	1	1.010	-	-		D352854at33208
OrthoFinder	1	1.000	-	-		FOG0004292
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101800
Panther	1	1.100	-	-	O	PTHR10698
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1635
SonicParanoid	1	1.000	-	-		X3548
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.740