Protein Alignment VhaSFD and Atp6v1h

DIOPT Version :9

• Sequence 1: NP_723992.1
• Gene: VhaSFD / 34997
• FlyBaseID: FBgn0027779
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_598587.2
• Gene: Atp6v1h / 108664
• MGIID: 1914864
• Length: 483
• Species: Mus musculus
• Alignment Length: 530
• Identity: 262/530 - (49%)
• Similarity: 350/530 - (66%)
• Gaps: 64/530 - (12%)

  Fly    12 IDMIAATSVLQQQAADIRTRTINWASYMQSQMISEEDYKAISALDKSRAS-----FLAQNSSQVV 71
            :|....|:::..:||::|...:||.||:|.||||.||.:.|...:..|:|     .|....||..
Mouse    10 VDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSSEDKQEMLQTEGSQCA 74

  Fly    72 KTLLNLVSHLSKDSTIQYILVLLDDLLQEDRSRVDLFHDTAGKLKQCIWGPFLNLLNRQDGFIVN 136
            ||.:||::|:||:.|:||||.::||:|||:..||.:|.|.|.:.|...|..||.:|||||.|.|:
Mouse    75 KTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVH 139

  Fly   137 MSSRILAKFACWGHETMPKSDLNFYLQFLKDQLASNGLAYLQEMAQLAKRTQTILVHTHGKDKDH 201
            |::||:||.|.||.|.|..||||:|..::|.||:|..|    ..:.:|..|.||
Mouse   140 MAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKL----RGSGVAVETGTI----------- 189

  Fly   202 HGHQYSPTLAQLQQQHELAERANESYREVGVGSDHQQQDGKCVIPNNEYIQSVARCLQMMLRVDE 266
                                          ..||           :::|:|.||.|||:||||:|
Mouse   190 ------------------------------SSSD-----------SSQYVQCVAGCLQLMLRVNE 213

  Fly   267 YRFAFVGVDGISTLIRILSTRVNFQVQYQLIFCLWVLTFNPLLAAKMNKFSVIPILADILSDCAK 331
            ||||:|..||::.::.:||.:..||:|||:||.:|:|.|:|.:...:.::::||:|:|||.:..|
Mouse   214 YRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVK 278

  Fly   332 EKVTRIILAVFRNLIEKPEDSSVAKDHCIAMVQCKVLKQLSILEQRRFDDEDITADVEYLSEKLQ 396
            |||||||||.|||.:||..:....:::.:||:||||||||..|||:::|||||:.|:::|.|||.
Mouse   279 EKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLG 343

  Fly   397 NSVQDLSSFDEYATEVRSGRLEWSPVHKSAKFWRENAQRLNEKNYELLRILVHLLETSKDAIILS 461
            .|||||||||||::|::||||||||||||.|||||||.||||||||||:||..|||.|.|..:|:
Mouse   344 ESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLA 408

  Fly   462 VACFDIGEYVRHYPRGKHVLEQLGGKQIVMQHLGHEDPNVRYEALLAVQKLMVHNWEYLGKQLEK 526
            ||..|:|||||||||||.|:|||||||:||.|:.|||..|||.||||||||||||||||||||:.
Mouse   409 VAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQS 473

  Fly   527 ENENQKQGAA 536
            |   |.|.||
Mouse   474 E---QPQTAA 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VhaSFD	NP_723992.1	VATPase_H	19..518	CDD:238159	247/503 (49%)
Atp6v1h	NP_598587.2	VATPase_H	17..465	CDD:238159	247/503 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834596
Domainoid	1	1.000	307	1.000	Domainoid score	I1343
eggNOG	1	0.900	-	-		E1_COG5231
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7139
Inparanoid	1	1.050	522	1.000	Inparanoid score	I1249
Isobase	1	0.950	-	0	Normalized mean entropy	S1675
OMA	1	1.010	-	-		QHG54625
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004292
OrthoInspector	1	1.000	-	-		oto95217
orthoMCL	1	0.900	-	-		OOG6_101800
Panther	1	1.100	-	-	LDO	PTHR10698
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1635
SonicParanoid	1	1.000	-	-		X3548
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740