Protein Alignment grp and PTK2

DIOPT Version :9

• Sequence 1: NP_477011.1
• Gene: grp / 34993
• FlyBaseID: FBgn0261278
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_012593.3
• Gene: PTK2 / 853522
• SGDID: S000003820
• Length: 818
• Species: Saccharomyces cerevisiae
• Alignment Length: 421
• Identity: 89/421 - (21%)
• Similarity: 160/421 - (38%)
• Gaps: 109/421 - (25%)

  Fly    28 LGEGAYGEV-KLLINRQTGEAVAMKMVDLKKHPDAANSVR---KEVCIQKML-QDKHILRFFGKR 87
            :|.|...|| |:..:.:..:..|:|.:::..|.......:   ||..|.|.| .:.||...|...
Yeast   261 IGSGGSSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLL 325

  Fly    88 SQGSVEYI-----FLEYAAGGELFDRIEPD--VGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLK 145
            ...:..|.     |:......:||..:|..  ..:|.:|....|.|:..|:.:.|..||||||||
Yeast   326 KVPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLK 390

  Fly   146 PENLLLDEHDNVKISDFGMATMFR------------CKGKERLLDKRCGTLPYVAPEVL------ 192
            |||:|:.:....|::|||::..:.            |:|       ..|:.||..|||:
Yeast   391 PENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQG-------MIGSPPYTPPEVMYFDAKK 448

  Fly   193 ------QKAYHAQPADLWSCGVILVTMLAGELPW-DQPSTNC------TEFTNW--RDNDHWQ-- 240
                  ||.|:....|.::.|::|:||:...:|: |..:|:.      ..:.|:  ..|.|::
Yeast   449 HYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNTDARFREFEVSYDNFINHQNPHFRDK 513

  Fly   241 ---LQTPWSKL-------DTLAISLLRKLLATSPGTRLTLEKTLDHKWCNM-------------- 281
               ...|.|:.       :|.|..:..:|...:|.||.|::...:..:...
Yeast   514 GCHKPGPGSEYSLARNFKNTDATRIAWRLADPNPATRYTMDDLFNDPFFQQIETCVEPNDDDLVR 578

  Fly   282 -----------QFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMP 335
                       .|::|  |.|.......:...:|..|::.|.|.......:.:|          |
Yeast   579 VPELRKSTSTNDFSEN--SLDAPHDQEVIHTSNPFLKKETLTSKPRSMLEIAES----------P 631

  Fly   336 TMRSDDDFNVRLGSGRSK-----EDGGDRQT 361
            :::......   .|.::|     ::||:..|
Yeast   632 SLKQKSKVK---DSAKTKTHDVGDEGGNEST 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	74/307 (24%)
		S_TKc	22..278	CDD:214567	74/306 (24%)
PTK2	NP_012593.3	S_TKc	259..562	CDD:214567	74/307 (24%)
		STKc_HAL4_like	261..562	CDD:270896	74/307 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010