DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment grp and CIPK9

DIOPT Version :9

Sequence 1:	NP_477011.1	Gene:	grp / 34993	FlyBaseID:	FBgn0261278	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_849571.1	Gene:	CIPK9 / 839349	AraportID:	AT1G01140	Length:	451	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	139/515 - (26%)
Similarity:	240/515 - (46%)	Gaps:	119/515 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ATREFVEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKK--HPDAANSVRKEVCIQKMLQ 76
            |:|..|..:.:.:|||||::.:||...|..||:..|:|::|.:|  .......:::|:...|:::
plant    11 ASRTRVGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREISTMKLIK 75

  Fly    77 DKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAH 141
            ..:::......:..:..||.||...||||||:|.....:.:.||:|||.||::.::|.|.||:.|
plant    76 HPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVDYCHSRGVYH 140

  Fly   142 RDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWS 205
            ||||||||:||.:..:|:||||::...|...::.||...|||..||||||| .|.|....||:||
plant   141 RDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTPNYVAPEVLSDKGYDGAAADVWS 205

  Fly   206 CGVILVTMLAGELPWDQPSTN------C-TEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATS 263
            |||||..::||.||:|:|:..      | .||:          ..||  ....|..:::::|..:
plant   206 CGVILFVLMAGYLPFDEPNLMTLYKRICKAEFS----------CPPW--FSQGAKRVIKRILEPN 258

  Fly   264 PGTRLTLEKTLDHKWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRN 328
            |.||:::.:.|:.:|                                              ..:.
plant   259 PITRISIAELLEDEW----------------------------------------------FKKG 277

  Fly   329 YCSQPMPTMRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNA 393
            |  :|....:.|:|..:        :|.....:.::|..::....:|..::...|.:  :.::.:
plant   278 Y--KPPSFDQDDEDITI--------DDVDAAFSNSKECLVTEKKEKPVSMNAFELIS--SSSEFS 330

  Fly   394 SQNYFQR---LVRRMTRFF-------VTTRWDDTIKRLVGTIERLGGYTCKF-----GDDGVVTV 443
            .:|.|::   ||::.|||.       :.::.::|.|.| |...|...|..|.     |..|.::|
plant   331 LENLFEKQAQLVKKETRFTSQRSASEIMSKMEETAKPL-GFNVRKDNYKIKMKGDKSGRKGQLSV 394

  Fly   444 STVDRNKLRLVFKA----HIIEMDGKILVDCRLSKGCGLEFKR---RFIK-IKNALEDIV 495
            :|.       ||:.    |::|:        |.:.|..|||.:   .|.| ..:.|:|:|
plant   395 ATE-------VFEVAPSLHVVEL--------RKTGGDTLEFHKVCDSFYKNFSSGLKDVV 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	95/268 (35%)
grp	NP_477011.1	S_TKc	22..278	CDD:214567	95/265 (36%)
CIPK9	NP_849571.1	S_TKc	19..274	CDD:214567	96/312 (31%)
		STKc_SnRK3	19..273	CDD:271133	95/265 (36%)
		CIPK_C	318..437	CDD:213380	31/136 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I1258
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001125
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960