DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment grp and CIPK20

DIOPT Version :9

Sequence 1:	NP_477011.1	Gene:	grp / 34993	FlyBaseID:	FBgn0261278	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_199394.1	Gene:	CIPK20 / 834622	AraportID:	AT5G45820	Length:	439	Species:	Arabidopsis thaliana

Alignment Length:	487	Identity:	136/487 - (27%)
Similarity:	231/487 - (47%)	Gaps:	87/487 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAA--NSVRKEVCIQKMLQDKHILRFF 84
            :.|.:.||:|.:.:|....|.:|||:||:|::|.:|.....  :.:::|:.:.::::..|::...
plant    12 YELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVRHPHVVFLH 76

  Fly    85 GKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENL 149
            ...:..:..|..:||..||||||::... .:.::.|::||.||:..::|.|.||:.|||||||||
plant    77 EVMASKTKIYFAMEYVKGGELFDKVSKG-KLKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENL 140

  Fly   150 LLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWSCGVILVTM 213
            ||||:.::||||||::.:...|.::.||...|||..||||||: :|.|....||:|||||:|..:
plant   141 LLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYDGAKADVWSCGVVLYVL 205

  Fly   214 LAGELPWDQPSTNCTEFTNWRDNDHWQLQTP-WSKLDTLAISLLRKLLATSPGTRLTLEKTLDHK 277
            |||.||:.:  .|..|.  :|.....:.:.| |...:..  .||.::|..:|.:|:.:||.:::.
plant   206 LAGFLPFHE--QNLVEM--YRKITKGEFKCPNWFPPEVK--KLLSRILDPNPNSRIKIEKIMENS 264

  Fly   278 WCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMPTMRSDDD 342
            |....|.               :|.:||:      ..:|..:.|...:...:..:||.....|
plant   265 WFQKGFK---------------KIETPKS------PESHQIDSLISDVHAAFSVKPMSYNAFD-- 306

  Fly   343 FNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQRLVRRMTR 407
                                     |..|.||...|..|                |::..|..::
plant   307 -------------------------LISSLSQGFDLSGL----------------FEKEERSESK 330

  Fly   408 FFVTTRWDDTIKRLVGTIERLGGYTCKF----GDDGVVTVSTVDRNKLRLVFKAHIIEMDGKI-L 467
            |  ||:.|  .|.:|...|.:...:.:|    .|.||......:..|..|.....|.|:.... :
plant   331 F--TTKKD--AKEIVSKFEEIATSSERFNLTKSDVGVKMEDKREGRKGHLAIDVEIFEVTNSFHM 391

  Fly   468 VDCRLSKGCGLEFKRRFI--KIKNALEDIVLK 497
            |:.:.|.|..:|:| :|.  :::.:|:|||.|
plant   392 VEFKKSGGDTMEYK-QFCDRELRPSLKDIVWK 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	92/260 (35%)
grp	NP_477011.1	S_TKc	22..278	CDD:214567	92/259 (36%)
CIPK20	NP_199394.1	STKc_SnRK3	11..265	CDD:271133	92/259 (36%)
		S_TKc	12..266	CDD:214567	92/260 (35%)
		CIPK_C	303..417	CDD:213380	30/161 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I1258
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960