Protein Alignment grp and SOS2

DIOPT Version :10

• Sequence 1: NP_477011.1
• Gene: grp / 34993
• FlyBaseID: FBgn0261278
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_198391.1
• Gene: SOS2 / 833502
• AraportID: AT5G35410
• Length: 446
• Species: Arabidopsis thaliana
• Alignment Length: 511
• Identity: 143/511 - (27%)
• Similarity: 235/511 - (45%)
• Gaps: 105/511 - (20%)

  Fly    22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVD----LKKHPDAANSVRKEVCIQKMLQDKHILR 82
            :.:.:|:|||.:.:||...|..||:.||:|::.    ||..  ..:.:::|:.|.|:::..:|:|
plant    11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNR--MVDQIKREISIMKIVRHPNIVR 73

  Fly    83 FFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPE 147
            .:...:..|..||.||:..||||||||.....:.:.|:::||.||:..:.:.|.:|:.|||||||
plant    74 LYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRDLKPE 138

  Fly   148 NLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQ-KAYHAQPADLWSCGVILV 211
            |||||.:.|:|:||||::.:.: :|.| ||...|||..|||||||. :.|....||:|||||||.
plant   139 NLLLDTNGNLKVSDFGLSALPQ-EGVE-LLRTTCGTPNYVAPEVLSGQGYDGSAADIWSCGVILF 201

  Fly   212 TMLAGELPW---DQP----STNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLT 269
            .:|||.||:   |.|    ..|..||:          ..||...:..  .|:.::|..:|.||:.
plant   202 VILAGYLPFSETDLPGLYRKINAAEFS----------CPPWFSAEVK--FLIHRILDPNPKTRIQ 254

  Fly   270 LEKTLDHKWCNMQF----ADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYC 330
            ::......|..:.:    |..|...:|.|..|..                       |.|..:|.
plant   255 IQGIKKDPWFRLNYVPIRAREEEEVNLDDIRAVF-----------------------DGIEGSYV 296

  Fly   331 SQPMPTMRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQ 395
            ::.:.  |:|:        |....:..:..||:|...||..|.:.
plant   297 AENVE--RNDE--------GPLMMNAFEMITLSQGLNLSALFDRR-------------------- 331

  Fly   396 NYFQRLVRRMTRFFVTTRWDDTIKRLVGTIERLG--GYTCKFGD--DGVVTVSTVDRNKLRLVFK 456
               |..|:|.|||.......:.|..:......:|  .:|..|..  :|   :|::...:|.:|.:
plant   332 ---QDFVKRQTRFVSRREPSEIIANIEAVANSMGFKSHTRNFKTRLEG---LSSIKAGQLAVVIE 390

  Fly   457 AHIIEMDGKILVDCRLSKGCGLEFKRRFIKIKNALEDIVLKGPTTWPIAIATNSVP 512
            .:.: .....:||.|.:.|..||:.:.:.|:.:.||:|:.:         ||..:|
plant   391 IYEV-APSLFMVDVRKAAGETLEYHKFYKKLCSKLENIIWR---------ATEGIP 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	98/268 (37%)
SOS2	NP_198391.1	Protein Kinases, catalytic domain	10..263	CDD:473864	98/267 (37%)
		CIPK_C	311..426	CDD:213380	28/141 (20%)