DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment grp and CIPK25

DIOPT Version :9

Sequence 1:	NP_477011.1	Gene:	grp / 34993	FlyBaseID:	FBgn0261278	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_568466.1	Gene:	CIPK25 / 832582	AraportID:	AT5G25110	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	128/493 - (25%)
Similarity:	223/493 - (45%)	Gaps:	95/493 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMV--DLKKHPDAANSVRKEVCIQKMLQDKHILRFF 84
            :.:.:.||:|.:|:|.......|||:||:|::  |..|.......:::|:.|.::::..:|:...
plant    43 YEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLVRHPNIVELK 107

  Fly    85 GKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENL 149
            ...:..:..:..:||..|||||.:|... .:.:..|::||.||:|.:::.|.||::|||||||||
plant   108 EVMATKTKIFFIMEYVKGGELFSKIVKG-KLKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENL 171

  Fly   150 LLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWSCGVILVTM 213
            |:||:.::|:||||::.:.....::.||..:|||..||||||| :|.|.....|:||||:||..:
plant   172 LVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYDGAKGDIWSCGIILYVL 236

  Fly   214 LAGELPWDQPS---------TNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLT 269
            |||.||:...:         .:..|:..|        .:|.||      .|:.|||...|..|::
plant   237 LAGFLPFQDENLMKMYRKIFKSEFEYPPW--------FSPESK------RLISKLLVVDPNKRIS 287

  Fly   270 LEKTLDHKWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPM 334
            :...:...|    |..|      ::|....:|           ....:.|..|::
plant   288 IPAIMRTPW----FRKN------INSPIEFKI-----------DELEIQNVEDET---------- 321

  Fly   335 PTMRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQ 399
            ||                        |.|..|..:.:...|...:.....:.|:...:.| :.|:
plant   322 PT------------------------TTATTATTTTTPVSPKFFNAFEFISSMSSGFDLS-SLFE 361

  Fly   400 RLVRRMTRFFVTTRWDDTIKRLVGTIERLGG----YTCKFGDDGVVTVSTVDRNKLRLVFKAHII 460
            .  :|..|...|:||  :...::|.:|.:|.    ...:..|..|......:..|.::...|.:.
plant   362 S--KRKLRSMFTSRW--SASEIMGKLEGIGKEMNMKVKRTKDFKVKLFGKTEGRKGQIAVTAEVF 422

  Fly   461 EMDGKILVDCRLSKGCG--LEFKRRFIK-IKNALEDIV 495
            |:..::.| ..|.|..|  ||:.|.:.: ::.|||:||
plant   423 EVAPEVAV-VELCKSAGDTLEYNRLYEEHVRPALEEIV 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	87/268 (32%)
grp	NP_477011.1	S_TKc	22..278	CDD:214567	87/267 (33%)
CIPK25	NP_568466.1	STKc_SnRK3	42..296	CDD:271133	87/267 (33%)
		S_TKc	43..297	CDD:214567	88/272 (32%)
		CIPK_C	342..455	CDD:213380	23/118 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I1258
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960