DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment grp and CIPK2

DIOPT Version :9

Sequence 1:	NP_477011.1	Gene:	grp / 34993	FlyBaseID:	FBgn0261278	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_196324.1	Gene:	CIPK2 / 830598	AraportID:	AT5G07070	Length:	456	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	132/499 - (26%)
Similarity:	227/499 - (45%)	Gaps:	99/499 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKK--HPDAANSVRKEVCIQKMLQDKHILR 82
            |.:.:.:.||:|.:.:|....:..|.|:||:||:|..|  ....:..:::|:.:.::.:..:::.
plant    10 ERYEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLSQQIKREISVMRIAKHPNVVE 74

  Fly    83 FFGKRSQGSVEYIFLEYAAGGELFDRI-----EPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHR 142
            .:...:..|..|..:||..|||||:::     :.||      |.:||.||:|.:::.|.||:.||
plant    75 LYEVMATKSRIYFVIEYCKGGELFNKVAKGKLKEDV------AWKYFYQLISAVDFCHSRGVYHR 133

  Fly   143 DLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWSC 206
            |:||||||||::||:|:||||::.:..||.::.||...|||..||||||: :|.|....||:|||
plant   134 DIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYEGTKADIWSC 198

  Fly   207 GVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTP-WSKLDTLAISLLRKLLATSPGTRLTL 270
            ||:|..:|||.||:.  .||..|.  :|.......:.| |...:..  .||.|:|..:..||:|:
plant   199 GVVLFVLLAGYLPFH--DTNLMEM--YRKIGKADFKCPSWFAPEVK--RLLCKMLDPNHETRITI 257

  Fly   271 EKTLDHKWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMP 335
            .|..:..|........::..:.::.....|..:|    .....|....||      .|:  :| |
plant   258 AKIKESSWFRKGLHLKQKKMEKMEKQQVREATNP----MEAGGSGQNENG------ENH--EP-P 309

  Fly   336 TMRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQR 400
            .:.:.:.|::                    ..||..|....|..|:.   ...:::.|||.....
plant   310 RLATLNAFDI--------------------IALSTGFGLAGLFGDVY---DKRESRFASQKPASE 351

  Fly   401 LVRRMTRFFVTTRWDDTIKRLVGTIERLGGYTCKF-----GDDGVVTVSTVDRNKLRLVFKAHII 460
            ::.::.         :..|.|...|.:.|....|.     |.:|::|
plant   352 IISKLV---------EVAKCLKLKIRKQGAGLFKLERVKEGKNGILT------------------ 389

  Fly   461 EMDGKI--------LVDCRLSKGCGLEFKRRFIK-IKNALEDIV 495
             ||.:|        ||:.:...|..:|:::...: ::.||.|||
plant   390 -MDAEIFQVTPTFHLVEVKKCNGDTMEYQKLVEEDLRPALADIV 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	94/267 (35%)
grp	NP_477011.1	S_TKc	22..278	CDD:214567	93/264 (35%)
CIPK2	NP_196324.1	PKc_like	11..265	CDD:419665	93/265 (35%)
CIPK2	NP_196324.1	CIPK_C	315..428	CDD:213380	24/163 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I1258
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960