DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment grp and KIN10

DIOPT Version :9

Sequence 1:	NP_477011.1	Gene:	grp / 34993	FlyBaseID:	FBgn0261278	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_850488.1	Gene:	KIN10 / 821259	AraportID:	AT3G01090	Length:	535	Species:	Arabidopsis thaliana

Alignment Length:	397	Identity:	119/397 - (29%)
Similarity:	183/397 - (46%)	Gaps:	50/397 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 AGTGP-AATREFVEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLK--KHPDAANSVRKEV 69
            :|||. :.....:..:.|.:|||.|::|.||:..:..||..||:|:::.:  |:.:....||:|:
plant    27 SGTGSRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREI 91

  Fly    70 CIQKMLQDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYL 134
            .|.::....||:|.:......:..|:.:||...|||||.|.....:.:.||:.:|.|::||:.|.
plant    92 KILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYC 156

  Fly   135 HQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQ-KAYHA 198
            |:..:.||||||||||||...||||:|||::.:.|   ....|...||:..|.||||:. |.|..
plant   157 HRNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMR---DGHFLKTSCGSPNYAAPEVISGKLYAG 218

  Fly   199 QPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATS 263
            ...|:|||||||..:|.|.||:|..:     ..|........:.|..|.|...|..|:.::|...
plant   219 PEVDVWSCGVILYALLCGTLPFDDEN-----IPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVD 278

  Fly   264 PGTRLTLEKTLDHKWCNMQFADNERSY------DLVDSAAALEICSPKAKRQRLQSSAHLSNGLD 322
            |..|:|:.:...|.|    |..:...|      |.|..|       .|...:.||...::  |.|
plant   279 PMKRVTIPEIRQHPW----FQAHLPRYLAVPPPDTVQQA-------KKIDEEILQEVINM--GFD 330

  Fly   323 DSISRNYCSQPMPTMRSDD---------DFNVRLGSG------RSKEDGGDRQTLAQEARLSYSF 372
                ||:..:.:.....:|         |...|..||      :...:|..|...|:......|.
plant   331 ----RNHLIESLRNRTQNDGTVTYYLILDNRFRASSGYLGAEFQETMEGTPRMHPAESVASPVSH 391

  Fly   373 SQPALLD 379
            ..|.|::
plant   392 RLPGLME 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	92/261 (35%)
grp	NP_477011.1	S_TKc	22..278	CDD:214567	92/258 (36%)
KIN10	NP_850488.1	STKc_AMPK_alpha	39..294	CDD:270981	93/266 (35%)
		S_TKc	42..294	CDD:214567	93/263 (35%)
		UBA_SnRK1_plant	316..356	CDD:270520	7/45 (16%)
		AMPKA_C	411..532	CDD:213378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010