DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment grp and CIPK3

DIOPT Version :9

Sequence 1:	NP_477011.1	Gene:	grp / 34993	FlyBaseID:	FBgn0261278	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_850095.2	Gene:	CIPK3 / 817240	AraportID:	AT2G26980	Length:	451	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	145/507 - (28%)
Similarity:	236/507 - (46%)	Gaps:	124/507 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVD---LKKHPDAANSVRKEVCIQKMLQDKHILRF 83
            :.:.:|:|||.:.:||...|.:|||.||:|::|   :.|| ..|..:|:|:...|:::..::::.
plant    24 YEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKH-KMAEQIRREIATMKLIKHPNVVQL 87

  Fly    84 FGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPEN 148
            :...:..:..:|.|||..||||||:|..|..|.:.||:|||.||:..::|.|.||:.||||||||
plant    88 YEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRGVYHRDLKPEN 152

  Fly   149 LLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWSCGVILVT 212
            ||||.:.|:||||||::.:.:....:.||...|||..||||||| .:.|....||:|||||:|..
plant   153 LLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYDGATADMWSCGVVLYV 217

  Fly   213 MLAGELPWDQPST------------NCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPG 265
            :|||.||:|..:.            ||               .||..|.  |:.|:.::|..:|.
plant   218 LLAGYLPFDDSNLMNLYKKISSGEFNC---------------PPWLSLG--AMKLITRILDPNPM 265

  Fly   266 TRLTLEKTLDHKWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYC 330
            ||:|.::..:.:|                                              ..::|
plant   266 TRVTPQEVFEDEW----------------------------------------------FKKDY- 283

  Fly   331 SQPMPTMRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQ 395
             :| |.....||.|:.......|:   ..:.|..|.|    ..|||.::...:.: |::..|. :
plant   284 -KP-PVFEERDDSNMDDIDAVFKD---SEEHLVTEKR----EEQPAAINAFEIIS-MSRGLNL-E 337

  Fly   396 NYF--QRLVRRMTRFFVTTRWDDTIKRLVGTIERLG------GY-----TCKFGDDGVVTVSTVD 447
            |.|  ::..:|.||..:....::.|:::....:.||      .|     ..|.|..|.:.|:|.
plant   338 NLFDPEQEFKRETRITLRGGANEIIEKIEEAAKPLGFDVQKKNYKMRLENVKAGRKGNLNVATE- 401

  Fly   448 RNKLRLVFKA----HIIEMDGKILVDCRLSKGCGLEFKRRFIKIKNALEDIV 495
                  :|:.    |::::.        .|||..|||.:.:.|:.|:||.:|
plant   402 ------IFQVAPSLHMVQVS--------KSKGDTLEFHKFYKKLSNSLEQVV 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	102/272 (38%)
grp	NP_477011.1	S_TKc	22..278	CDD:214567	102/271 (38%)
CIPK3	NP_850095.2	STKc_SnRK3	23..278	CDD:271133	102/271 (38%)
		S_TKc	24..279	CDD:214567	103/318 (32%)
		CIPK_C	323..432	CDD:213380	25/125 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I1258
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001125
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.960