DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment grp and CIPK16

DIOPT Version :9

Sequence 1:	NP_477011.1	Gene:	grp / 34993	FlyBaseID:	FBgn0261278	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_180081.1	Gene:	CIPK16 / 817047	AraportID:	AT2G25090	Length:	469	Species:	Arabidopsis thaliana

Alignment Length:	503	Identity:	130/503 - (25%)
Similarity:	220/503 - (43%)	Gaps:	106/503 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMV---DLKKHPDAANSVRKEVCIQKMLQDKHILRF 83
            :.:.:.||.|.:.:|.......||:.||:|::   .:.|.......:.:|:.:.::|:..:::..
plant    15 YNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLRHPNVVEL 79

  Fly    84 FGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPEN 148
            ....:.....:..:||..|||||:.|:.|..:|:..|::||.||:|.:::.|.||:.|||:||||
plant    80 REVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRGVFHRDIKPEN 144

  Fly   149 LLLDEHDNVKISDFGMATMFRCKG-------KERLLDKRCGTLPYVAPEVLQ-KAYHAQPADLWS 205
            ||||...::|::|||::.:...:|       .:.||..||||..|||||||: |.|....||:||
plant   145 LLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAPEVLRNKGYDGAMADIWS 209

  Fly   206 CGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQT----------PWSKLDTLAISLLRKLL 260
            ||::|..:|||.||             :.|.:...|.|          ||..|::.  .||.:||
plant   210 CGIVLYALLAGFLP-------------FIDENVMTLYTKIFKAECEFPPWFSLESK--ELLSRLL 259

  Fly   261 ATSPGTRLTLEKTLDHKWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSI 325
            ...|..|:::.:.....|....|..:                              ::..:|::|
plant   260 VPDPEQRISMSEIKMIPWFRKNFTPS------------------------------VAFSIDETI 294

  Fly   326 SRNYCSQP-MPTMRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQ 389
            .    |.| .||.:...|.|       .|||.|               :.|...:.....|.|:.
plant   295 P----SPPEPPTKKKKKDLN-------EKEDDG---------------ASPRSFNAFQFITSMSS 333

  Fly   390 TQNASQNYFQRLVRRMTRFFVTTRWDDTIKRLVGTIERLGGYTCKFGDDGVVTVS-TVDRNKLRL 453
            ..:.| |.|: :.|:..|.|.:.....::|..:.|..|......|...|..:.:. ..:..|.||
plant   334 GFDLS-NLFE-IKRKPKRMFTSKFPAKSVKERLETAAREMDMRVKHVKDCKMKLQRRTEGRKGRL 396

  Fly   454 VFKAHIIEMDGKILV--DCRLSKGCGLEFKRRFI----KIKNALEDIV 495
            ...|.:.|:..::.|  .|:.| |..||:   ::    .::.||:|||
plant   397 SVTAEVFEVAPEVSVVEFCKTS-GDTLEY---YLFCEDDVRPALKDIV 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	86/277 (31%)
grp	NP_477011.1	S_TKc	22..278	CDD:214567	86/276 (31%)
CIPK16	NP_180081.1	PKc_like	14..277	CDD:419665	86/276 (31%)
CIPK16	NP_180081.1	CIPK_C	323..437	CDD:213380	25/119 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I1258
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960