Protein Alignment grp and CG4629

DIOPT Version :10

• Sequence 1: NP_477011.1
• Gene: grp / 34993
• FlyBaseID: FBgn0261278
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Alignment Length: 495
• Identity: 121/495 - (24%)
• Similarity: 215/495 - (43%)
• Gaps: 94/495 - (18%)

  Fly    28 LGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVR---KEVCIQKMLQDKHILRFFG-KRS 88
            :|.|.:.:|||.:::.|.:.||:|:|||.:....|.::|   .|:...:.:...:|||.|. ..:
  Fly    72 IGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRLFEVVET 136

  Fly    89 QGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDE 153
            .|.| |:..|:..||||::.|.....:.:..|.....|||..:.::|..|..|||:|.||:||..
  Fly   137 LGRV-YLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLS 200

  Fly   154 HDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWSCGVILVTMLAGE 217
            .|.:|::|||.:|.. ..|..:.||..||:.||.|||:. ...|...|.|:|:.|::|..|:.|.
  Fly   201 EDRLKLADFGFSTQL-INGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGN 264

  Fly   218 LPWDQPSTNCTEFTNWRDNDH---WQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEKTLDHKWC 279
            :|:..|:....:....: .|:   .||..|       .|.|::::|...|..|.|::..|:.::.
  Fly   265 MPFRAPTIPGLKAAILK-GDYLLPGQLSLP-------CIRLIQRILIHIPAQRPTIDDMLNSQFV 321

  Fly   280 N--------MQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMPT 336
            .        ||:..|:.:..:..|     |...::|..||:.||.|.:...:.:.:...|  |.|
  Fly   322 TCPKLSADLMQWEINQHTKPVKRS-----IFWVRSKSHRLRKSASLRDRYAEVVKKPAIS--MNT 379

  Fly   337 MRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQRL 401
            .:.|:.|               .|...|...:.:....|       :::|:.:.|:..|
  Fly   380 RQQDEMF---------------VQNFLQPIEMGHELLVP-------VSSQLKEPQSTEQ------ 416

  Fly   402 VRRMTRFF---------VTTRWDDTIKRLVGTIERLG-------------------GYTCKFGDD 438
            .:|.||.:         ||....:..|:|....:.:|                   .|..:.|..
  Fly   417 AKRPTRRYMFCGSLKKKVTPMETEPEKQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGSC 481

  Fly   439 GVVTVSTVDRNKL-RLVFKAHII----EMDGKILVDCRLS 473
            .::..:|.|.::| .|.|:|..|    .:..::|::.|.|
  Fly   482 VMLPTNTEDLSQLGALEFEARQILAELGLTSEMLINARQS 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	79/258 (31%)
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	79/258 (31%)