Protein Alignment grp and Smokl6

DIOPT Version :10

• Sequence 1: NP_477011.1
• Gene: grp / 34993
• FlyBaseID: FBgn0261278
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_063124246.1
• Gene: Smokl6 / 102555239
• RGDID: 7726443
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 354
• Identity: 94/354 - (26%)
• Similarity: 151/354 - (42%)
• Gaps: 66/354 - (18%)

  Fly    22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHILRFFGK 86
            :.:..::..|.:|.|||..:|:|...||:|.:.:.:.  ....:..||.|.|||...:|:..:..
  Rat    14 YKMLSSIDHGEFGTVKLACHRKTEALVAIKTIQITER--RIKRILSEVSILKMLHHPNIICLYQV 76

  Fly    87 RSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLL 151
            .......::..|:|.||.|:|.|..|..:.:..|::.|.|::|.:.|.|...|.|||:||:|::.
  Rat    77 LVTAKHVHLVTEFAPGGNLYDLIIEDGPLQEEVAKKKFGQIVSAIKYCHTLDIVHRDIKPQNIVE 141

  Fly   152 DEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEV-LQKAYHAQPADLWSCGVILVTMLA 215
            ||...:|:.|||:|...|   ...||..:|||..:.|||: |.:.|..:.:|:||.||:|..|.|
  Rat   142 DEDGLMKVIDFGLAAHQR---PGTLLSGKCGTKRFAAPEILLGEPYDGKKSDVWSLGVLLYFMTA 203

  Fly   216 GELPWDQPSTNCTEFTNWRDNDHW-QLQTPWSKLDTLAI---------SLLRKLLATSPGTRLTL 270
            |.:|          |....|.|.. ::.|     .|.||         :|:.::|......|..:
  Rat   204 GFVP----------FQRVTDKDTGEEIVT-----QTYAIPSHFSGQLENLIHQMLTVPIEKRPFI 253

  Fly   271 EKTLDHKW----------------------CNMQFADNERSYDLVDS------AAALEICSPKAK 307
            |...:|.|                      |.|.|..:|....|.:.      .|.|.:...:.|
  Rat   254 EAIEEHPWVIKSELNMSPKTYPDTQIIDVLCGMGFNASEIRESLKNQKFDEPMGAYLILKEQEDK 318

  Fly   308 RQRLQSSAHLSNGLDDSISRNYCSQPMPT 336
            |...:|       :..|...|.|..|.|:
  Rat   319 RVEYRS-------ITSSKPLNLCPTPSPS 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	79/289 (27%)
Smokl6	XP_063124246.1	None