Protein Alignment grp and LOC100485259

DIOPT Version :10

• Sequence 1: NP_477011.1
• Gene: grp / 34993
• FlyBaseID: FBgn0261278
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_002933099.1
• Gene: LOC100485259 / 100485259
• XenbaseID: XB-GENE-29077711
• Length: 605
• Species: Xenopus tropicalis
• Alignment Length: 488
• Identity: 128/488 - (26%)
• Similarity: 218/488 - (44%)
• Gaps: 99/488 - (20%)

  Fly    22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSV--RKEVCIQKMLQDKHILRFF 84
            :.|.:|||.|.||:||....:.||:.||:|.:...|..|..:.|  ::|:.|..:||.:||:|.|
 Frog    68 YELLETLGRGTYGKVKRATEKATGKMVAVKSIQKDKITDERDRVHLQREIEITALLQHEHIIRVF 132

  Fly    85 GKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENL 149
            ..........|.:|||:.|||:|.|.....:|:::|:|:|.|::|.::|.|::||.|||:|.||:
 Frog   133 EVFESRDKIIIVMEYASNGELYDFINNKHQIPENDARRFFRQIVSAVHYCHKKGIVHRDIKLENI 197

  Fly   150 LLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQ-KAYHAQPADLWSCGVILVTM 213
            |||::.|||::|||::..|:   |.::|:..||:..|.:||::: ..|.....|.|:.||:|..:
 Frog   198 LLDDNLNVKLADFGLSNHFQ---KHQVLETYCGSPLYASPEIVKGLPYQGPEVDCWALGVLLYAL 259

  Fly   214 LAGELPWDQPSTNCTEFT------NWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEK 272
            :.|.:|::  ::|.....      .:|:..|.          :.|..|:..:|..:..:|.|:|.
 Frog   260 VYGIMPFE--NSNYKSLAEQISRGQYREPPHL----------SGAFGLVDWMLTVNTSSRATIED 312

  Fly   273 TLDHKWCN--------------------------------MQFADNERSYDLVDSAAALEICSPK 305
            ..:|.|.|                                .|....|...|.:......|:|..|
 Frog   313 IANHWWVNWGYDTVVCDCELAPECHSPLLARYIECQNTQGFQMTTMEHQQDELRKEEEYEVCLRK 377

  Fly   306 AKRQR--LQS------------------------SAHL-SNGLDDSISRNYC------SQPMPTM 337
            :|::.  :||                        ||.| |:.|.:...:| |      ||..|..
 Frog   378 SKKENDIIQSQQEIDLNNTIQIPKGILKKRSSFDSAFLTSSNLSEERPQN-CTQVNKDSQSPPLY 441

  Fly   338 RSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLAT--QMNQTQNASQNYFQR 400
            .:....|........|:  |..:..:.|....||.|...::......|  |:.|.:..|:|.|:|
 Frog   442 STVSPINTEAIFKMPKK--GILKKTSYERESGYSSSPERIMSTECPKTSHQVLQNKRRSENEFKR 504

  Fly   401 ---LVRRMTRFFVT--TRWDDTIKRLVGTIERL 428
               :::...||..|  ...|.::..|.|::|.|
 Frog   505 KKGILKTTGRFSGTLDAAGDGSVNSLSGSLEDL 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	85/265 (32%)
LOC100485259	XP_002933099.1	STKc_NUAK	67..319	CDD:270975	85/265 (32%)