Protein Alignment grp and chek1

DIOPT Version :9

• Sequence 1: NP_477011.1
• Gene: grp / 34993
• FlyBaseID: FBgn0261278
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_002937561.2
• Gene: chek1 / 100038224
• XenbaseID: XB-GENE-491846
• Length: 474
• Species: Xenopus tropicalis
• Alignment Length: 496
• Identity: 222/496 - (44%)
• Similarity: 315/496 - (63%)
• Gaps: 53/496 - (10%)

  Fly    18 FVEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHILR 82
            |||.|.|.|||||||||||:|.:||:|.||||:|:||:.:..|...:::||:||.:||...:|:|
 Frog     5 FVEDWDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAADCPENIKKEICINRMLNHTNIVR 69

  Fly    83 FFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPE 147
            |:|.|.:|:::|:||||..|||||||||||||||:.:||::|.||::|:.|||..||.|||:|||
 Frog    70 FYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGITHRDIKPE 134

  Fly   148 NLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQ-KAYHAQPADLWSCGVILV 211
            |||||:.|::||||||:||:||...|||||:|.||||||||||::: :|::|:|.|:||||::|.
 Frog   135 NLLLDDRDHLKISDFGLATVFRHNAKERLLNKMCGTLPYVAPELIKSRAFNAEPVDVWSCGIVLT 199

  Fly   212 TMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEKTLDH 276
            .|||||||||||:..|.|:.:|::.:|:  .|||.|:....::||.|:|..:|.:|:|:......
 Frog   200 AMLAGELPWDQPTEACQEYCDWKEKNHY--LTPWKKIGATPLALLCKMLTENPQSRITIPDIKKD 262

  Fly   277 KWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMPTMRSDD 341
            :|..                   |:.....||.|.     .|.|..|  |...|.|    :|||.
 Frog   263 RWFT-------------------ELIKKGIKRSRA-----FSGGTSD--SSGLCKQ----IRSDM 297

  Fly   342 DFNV-----------------RLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQ 389
            :.::                 |........:|.....|.|...:  ||||||..:::||::|:..
 Frog   298 EISIISHSEEKNAYSSTQPEPRTALATWDSNGSHIDNLVQGKGI--SFSQPACPENMLLSSQLIG 360

  Fly   390 TQNASQNYFQRLVRRMTRFFVTTRWDDTIKRLVGTIERLGGYTCKFGDDGVVTVSTVDRNKLRLV 454
            |..:|||.:||||:||||||.....:.:...|:.|.|:: ||..|......||:||.||...:|:
 Frog   361 TPGSSQNVWQRLVKRMTRFFTKVDAESSYSNLMDTCEKM-GYVLKKSCANQVTLSTTDRRNNKLI 424

  Fly   455 FKAHIIEMDGKILVDCRLSKGCGLEFKRRFIKIKNALEDIV 495
            ||.:::||:.:||:|.|||||.||||||.|:|||..::.||
 Frog   425 FKVNLVEMEDRILLDFRLSKGDGLEFKRHFLKIKKKMDAIV 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	142/259 (55%)
		S_TKc	22..278	CDD:214567	141/256 (55%)
chek1	XP_002937561.2	STKc_Chk1	7..265	CDD:270971	142/259 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	320	1.000	Domainoid score	I1239
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H975
Inparanoid	1	1.050	421	1.000	Inparanoid score	I1752
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343319at33208
OrthoFinder	1	1.000	-	-		FOG0001125
OrthoInspector	1	1.000	-	-		oto103095
Panther	1	1.100	-	-	LDO	PTHR24343
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2646
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160