| Sequence 1: | NP_001137830.2 | Gene: | Trpgamma / 34991 | FlyBaseID: | FBgn0032593 | Length: | 1188 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_536321.1 | Gene: | Trpc4 / 84494 | RGDID: | 621276 | Length: | 977 | Species: | Rattus norvegicus |
| Alignment Length: | 1026 | Identity: | 451/1026 - (43%) |
|---|---|---|---|
| Similarity: | 623/1026 - (60%) | Gaps: | 134/1026 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 77 QLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINY 141
Fly 142 NVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWES------ASEDTSTFTPDITPLILA 200
Fly 201 AHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSK 265
Fly 266 DPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNHDPTGPVYE 330
Fly 331 HGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFS 395
Fly 396 LAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEEL 460
Fly 461 PTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSF 525
Fly 526 FQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRM 590
Fly 591 VMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFS 655
Fly 656 NLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLI 720
Fly 721 SERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTI 785
Fly 786 RRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAES-QGVTEDDVNEIKQDISAFRCELVEILKNS 849
Fly 850 GMDTNVTAGQGGG-------------GGKKNRQKERRLMKGFNIAPPGSTGSLAPVAEFSTSLDN 901
Fly 902 YDNQHEILSSTLSTLFTP-------NFM---------HKRQQSQAGSGGGG-----SESPTTPTA 945
Fly 946 PQG--------TQGAAMTASSQVTKYNKSALKPYNKRIAGHKKRWGTLIEAAKVGNVSKMLGRSK 1002
Fly 1003 SEDSVCNSSHTSTPVHGQMRVTYAQNSPQQEYGYHGETSSTTISTPTPTIS 1053 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Trpgamma | NP_001137830.2 | trp | 77..841 | CDD:273311 | 405/770 (53%) |
| ANK | 113..>217 | CDD:238125 | 59/109 (54%) | ||
| ANK repeat | 118..147 | CDD:293786 | 19/28 (68%) | ||
| ANK repeat | 175..217 | CDD:293786 | 22/47 (47%) | ||
| TRP_2 | 227..286 | CDD:285535 | 42/58 (72%) | ||
| RRT14 | <778..892 | CDD:293680 | 42/127 (33%) | ||
| Trpc4 | NP_536321.1 | trp | 17..749 | CDD:273311 | 405/770 (53%) |
| ANK 1 | 31..60 | 11/28 (39%) | |||
| ANK | 64..>168 | CDD:238125 | 60/111 (54%) | ||
| ANK 2 | 69..97 | 19/27 (70%) | |||
| Multimerization domain. /evidence=ECO:0000250 | 87..172 | 43/92 (47%) | |||
| ANK repeat | 122..167 | CDD:293786 | 23/44 (52%) | ||
| TRP_2 | 176..235 | CDD:285535 | 42/58 (72%) | ||
| Multimerization domain. /evidence=ECO:0000250 | 254..304 | 27/49 (55%) | |||
| Binds to ITPR1, ITPR2 and ITPR3. /evidence=ECO:0000250 | 615..977 | 120/389 (31%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 767..790 | 2/22 (9%) | |||
| PDZ-binding domain. /evidence=ECO:0000250 | 975..977 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166341882 | |
| Domainoid | 1 | 1.000 | 274 | 1.000 | Domainoid score | I1701 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3609 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H22955 | |
| Inparanoid | 1 | 1.050 | 801 | 1.000 | Inparanoid score | I473 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D355630at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000660 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm8940 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102173 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR10117 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X802 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.800 | |||||