Protein Alignment Trpgamma and trpc5b

DIOPT Version :10

• Sequence 1: NP_001137830.2
• Gene: Trpgamma / 34991
• FlyBaseID: FBgn0032593
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_073791538.1
• Gene: trpc5b / 559586
• ZFINID: ZDB-GENE-091112-24
• Length: 1026
• Species: Danio rerio
• Alignment Length: 798
• Identity: 407/798 - (51%)
• Similarity: 551/798 - (69%)
• Gaps: 71/798 - (8%)

  Fly    71 PHQEIR---QLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENL 132
            |.|.:|   :|:.:|:.:|.|||:||.||.::.|::|.....|||||:|||||:|||:||:||||
Zfish    22 PLQIVRAEVELSAKERAYLTAVEKGDYAGVKQALEEADIYYNINVNCLDPLGRSALLIAIENENL 86

  Fly   133 EMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDT--STFTPDIT 195
            |::|||:::.|.|.||||::|.:|.|.|||:||.:....    |.....|...||  |.||||||
Zfish    87 EVMELLLSHGVHTGDALLYAIRKEVVGAVELLLSYRKPC----GEKQVPSLMMDTQFSEFTPDIT 147

  Fly   196 PLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLI 260
            |::||||.:||||||:|:.|...:|.||.:||.|.|||.|.:.|||||||||:|.|:||||||||
Zfish   148 PIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLI 212

  Fly   261 ALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNH-DP 324
            ||||:|||||||.|.|||:.||.:|:||:.||.||.:||:.||..|||..|:|.|||.:||| |.
Zfish   213 ALSSEDPILTAFRLGWELKELSKVENEFRQEYDELSQQCKLFAKDLLDQARSSRELETILNHRDD 277

  Fly   325 TGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGI 389
            .....:.||...|.:||||||..||:|||..|.|||||::||:|.||:||::.|::.|....||:
Zfish   278 HSEELDLGECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVTCFIIGL 342

  Fly   390 MFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGML 454
            :||:||:.|:|||.|::|..::|||||||||:|||.||||||:||||.|
Zfish   343 LFPVFSIIYLLAPKSTLGTFIKKPFIKFICHTASYLTFLFLLLLASQHI---------------- 391

  Fly   455 NTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVA 519
             ...:|.. :|..|||:||:||.||.|.||:|:|::||.|..||::|.||::||..||||:||::
Zfish   392 -VQTDLHV-QGPPPTFVEWMILPWVLGFIWAEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATIS 454

  Fly   520 LRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQ 584
            |::|::|:      |||   ..||..|:.|.|.||:|.||:.|||||||:|:.:|:.|.||||||
Zfish   455 LKMVAYFK------YNS---SRPRVEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQ 510

  Fly   585 VSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACI 649
            :||.||::||:||.|:|.|||.||.:|||||.:||   |.|               .:.:||.|.
Zfish   511 ISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY---ETK---------------ASEEPNNCK 557

  Fly   650 VWR------RFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNL 708
            ..|      .||.||||.|:|||:||||::|....:.....||.|.|..|||||:||::|||||:
Zfish   558 GIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNM 622

  Fly   709 LIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSG 773
            ||||||:|||||::.||:||||||:|||:|||:||||.||||||||:|||:||...|:....| |
Zfish   623 LIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSVWYLCVWLHCRLC-G 686

  Fly   774 SSAARRE----HLKTIRRKAQQASD---RDFKYQQIMRNLVRRYVTVEQRKAES-QGVTEDDVNE 830
            ....|.|    | |.::...::.:|   ::..||:::||||:|||....|.|:: :|:||::..|
Zfish   687 HGEPRHEDKCKH-KNLKEFTERHADNLIQNQHYQEVIRNLVKRYVAAMIRSAKTDEGLTEENFKE 750

  Fly   831 IKQDISAFRCELVEILKN 848
            :|||||:||.|::::|.|
Zfish   751 LKQDISSFRYEVLDLLGN 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trpgamma	NP_001137830.2	trp	77..841	CDD:273311	401/780 (51%)
		ANK repeat	118..147	CDD:293786	18/28 (64%)
		ANK repeat	175..217	CDD:293786	24/43 (56%)
		TRP_CaM_bind1	865..>891	CDD:467881
trpc5b	XP_073791538.1	None