DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trpgamma and zgc:110224

DIOPT Version :9

Sequence 1:	NP_001137830.2	Gene:	Trpgamma / 34991	FlyBaseID:	FBgn0032593	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_001017642.1	Gene:	zgc:110224 / 550335	ZFINID:	ZDB-GENE-050417-120	Length:	403	Species:	Danio rerio

Alignment Length:	399	Identity:	78/399 - (19%)
Similarity:	130/399 - (32%)	Gaps:	125/399 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VSPARRKSVLAPILNKIKNG----ADAADSAEKKLGSESSGSGHIAVQIEPARRVKRHSIHGMME 64
            ::|.:.|.:::......:||    .|.:||:...|.|....:|.:.|:::    :::.|..|.::
Zfish     1 MAPVKIKHIVSFTSQDSRNGVCNLCDGSDSSRPWLCSVQDRTGVLRVELQ----MEKVSAIGFID 61

  Fly    65 EENTIRPHQEI---RQLTLEEKKFLLAV-----------ERGDMAGTRRMLQKA--------QDT 107
            ..|......::   |.....:..|:..:           ::|......||.:||        :..
Zfish    62 VGNYGSAFIQVDVGRSSWSSDHPFVTLLPTATLMSPADSKQGTGRQNVRMFKKADFLSRAAEESW 126

  Fly   108 EYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTF 172
            :.:.|.|..|..:.. ...:....:..||      .||:|:     ||:..:..|.|...|.::.
Zfish   127 DRMRVTCTQPFNKHT-QFGLSFLRIRTVE------DDTEDS-----SEQQEDTPENLRTPEKMSS 179

  Fly   173 HSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQ 237
            ..|    |.|:....:||...||                                |.......|.
Zfish   180 VME----WLSSPAVQNTFFGRIT--------------------------------GDGSSEAQRN 208

  Fly   238 EDSLRHSRSRINA----YRALA-SPSLIALS--------SKDPILTAFELSWELRRLSFLEHEFK 289
            ..||..:...:.|    .|:|: ||...|.|        ||.| ...|..|.||.:..
Zfish   209 AGSLSRAERMVKAAQLKRRSLSTSPCSTASSTTPQREDNSKSP-PGGFTTSGELVKTP------- 265

  Fly   290 NEYQELRKQCQDFATALLDHTRTSHELEILLNHD-------PTGPVYEHGERMHLNRLKLAIKLR 347
               ||.|              |.....:||||.|       |||..::|.....|.|.:  .:.|
Zfish   266 ---QEQR--------------RKPKARQILLNSDTPLKRSRPTGSTHDHPTSPKLPRSQ--AEAR 311

  Fly   348 QKKFVAHSN 356
            ||...|..:
Zfish   312 QKPIDAQDS 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trpgamma	NP_001137830.2	trp	77..841	CDD:273311	63/319 (20%)
		ANK	113..>217	CDD:238125	19/103 (18%)
		ANK repeat	118..147	CDD:293786	4/28 (14%)
		ANK repeat	175..217	CDD:293786	7/41 (17%)
		TRP_2	227..286	CDD:285535	18/71 (25%)
		RRT14	<778..892	CDD:293680
zgc:110224	NP_001017642.1	XRCC1_N	1..149	CDD:280080	24/152 (16%)
zgc:110224	NP_001017642.1	zf-C2HC_2	369..391	CDD:290624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3609
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900