Protein Alignment Trpgamma and Trpc7

DIOPT Version :9

• Sequence 1: NP_001137830.2
• Gene: Trpgamma / 34991
• FlyBaseID: FBgn0032593
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_017455952.1
• Gene: Trpc7 / 282822
• RGDID: 628820
• Length: 904
• Species: Rattus norvegicus
• Alignment Length: 859
• Identity: 309/859 - (35%)
• Similarity: 453/859 - (52%)
• Gaps: 179/859 - (20%)

  Fly    55 KRHSIHG---MMEEENTIRPHQEIRQLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVD 116
            :|.:|.|   |..|:.|        .||.||::||.:.|.|::...|:||   ::::.:|.||||
  Rat   119 RRQAIRGPAYMFNEKGT--------SLTPEEERFLDSAEYGNIPVVRKML---EESKTLNFNCVD 172

  Fly   117 PLGRTALLMAIDNENLEMVELLINYN--VDTKDALLHSISEEFVEAVEVLLDH------ENVTF- 172
            .:|:.||.:|:.||:||:.|||:...  ....||||.:||:.:|..||.:|.|      :.:|.
  Rat   173 YMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILSHPAFAQGQRLTLS 237

  Fly   173 ---HSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQ 234
               ....:..:.:..||.:.|:.||||:|||||...|||:.|||.:||.:..|||..|.|:||.:
  Rat   238 PLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTE 302

  Fly   235 SRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQC 299
            .:::||..|||||:|||:.|||.:.::|||:||:|||.|||.||.||:.:|.||||:|::|..||
  Rat   303 KQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQC 367

  Fly   300 QDFATALLDHTRTSHELEILLNHDPTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASI 364
            :||...:||..|.:.|:|.:||.|....|:....|..|:|:|||||...||
  Rat   368 KDFVVGVLDLCRDTEEVEAILNGDVNLQVWSDHHRPSLSRIKLAIKYEVKK-------------- 418

  Fly   365 WYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLF 429
                                                     :|:|:|.||:||:.|:.|:..||.
  Rat   419 -----------------------------------------LGRTLRSPFMKFVAHAVSFTIFLG 442

  Fly   430 LLML-ASQRIETFIGGWFFADSSGMLNTMEELPTKR---------GAKPTFIEW---LILAWVSG 481
            ||:: ||.|.|                .::.||.:.         ..|.|...|   ||:.||.|
  Rat   443 LLVVNASDRFE----------------GVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLG 491

  Fly   482 LIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIY--------NSHA 538
            :||||.|::|:.|.:||:..:||::||...|::||:...|.::|.:..:..:|        ..|.
  Rat   492 MIWSECKEIWEEGPREYVLHLWNLLDFGMLSVFVASFTARFMAFLKASEAQLYVDQYVQDVTLHN 556

  Fly   539 TDLP---------RERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDI 594
            ..||         |::|...||.:|||||::.|.:.|..::.||...|...||||:||.|.|.||
  Rat   557 VSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDI 621

  Fly   595 MKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFE 659
            .||..::::|..||..|:..|..||      |..:.:|                    .|:.:.|
  Rat   622 FKFMVIFIMVFVAFMIGMFNLYSYY------RGAKYNP--------------------AFTTVEE 660

  Fly   660 TTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERA 724
            :.:||||::|||.::.|..|.....|....|.:::|.|:|..:|||||:||||:|:|||.|.|.|
  Rat   661 SFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDA 725

  Fly   725 DVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFC----SGSSAARREH---- 781
            ||||||||:|||:|||:||.|.|.|||::|:|||.:|.|  ||...|    ..|.|.|.|:
  Rat   726 DVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLI--MRIKMCLIKLCKSKAKRCENDLEM 788

  Fly   782 --LKTIRRKAQ-QASDRD-------------FKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNE 830
              |.:..||.: ||..|:             .:||:||:.|::|||...|...|:..|.|.::.|
  Rat   789 GMLNSKFRKTRYQAGMRNSENLTANSTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKE 853

  Fly   831 IKQDISAFRCELVE 844
            ||||||:.|.||:|
  Rat   854 IKQDISSLRYELLE 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trpgamma	NP_001137830.2	trp	77..841	CDD:273311	300/829 (36%)
		ANK	113..>217	CDD:238125	45/115 (39%)
		ANK repeat	118..147	CDD:293786	11/30 (37%)
		ANK repeat	175..217	CDD:293786	18/41 (44%)
		TRP_2	227..286	CDD:285535	32/58 (55%)
		RRT14	<778..892	CDD:293680	31/87 (36%)
Trpc7	XP_017455952.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3609
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.770