Protein Alignment Trpgamma and Trpgamma

DIOPT Version :10

• Sequence 1: NP_001137830.2
• Gene: Trpgamma / 34991
• FlyBaseID: FBgn0032593
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_061512371.1
• Gene: Trpgamma / 1277541
• VectorBaseID: AGAMI1_008961
• Length: 1363
• Species: Anopheles gambiae
• Alignment Length: 1184
• Identity: 816/1184 - (68%)
• Similarity: 912/1184 - (77%)
• Gaps: 104/1184 - (8%)

  Fly    52 RRVKRHSIHGMMEEENTIRPHQEIRQLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVD 116
            :|||||||||||||||.:||||||..|:|||||:||||||||:|.|||:|:||:...:||:||||
Mosquito   115 KRVKRHSIHGMMEEENVVRPHQEIGALSLEEKKYLLAVERGDVATTRRILEKAEAESHININCVD 179

  Fly   117 PLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWE 181
            ||||:|||||||||||||||||||:.|||||||||:||||||||||||||||:....|...||||
Mosquito   180 PLGRSALLMAIDNENLEMVELLINHRVDTKDALLHAISEEFVEAVEVLLDHEDSCHKSGDPHSWE 244

  Fly   182 SASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRS 246
            :...||:|||||||||||||||||||||||||||||.||||||||||||:||.||.|||||||||
Mosquito   245 ALPPDTATFTPDITPLILAAHRDNYEIIKILLDRGATLPMPHDVRCGCDDCVTSRMEDSLRHSRS 309

  Fly   247 RINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTR 311
            |||||||||||||:||||||||||||||||||||||||||||||||||||:||||||||||||||
Mosquito   310 RINAYRALASPSLVALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRRQCQDFATALLDHTR 374

  Fly   312 TSHELEILLNHDPTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKN 376
            :|||||:|||||||||.:|||:||||||||||:||||||||:|.|||||||||||||||||||||
Mosquito   375 SSHELEVLLNHDPTGPAFEHGDRMHLNRLKLAVKLRQKKFVSHPNVQQLLASIWYEGLPGFRRKN 439

  Fly   377 MALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETF 441
            |||||::|:|||||||:||.:||:||:||:||||||||||||||||||||||||||||||||||.
Mosquito   440 MALQALEIVRIGIMFPLFSFSYIIAPHSSLGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETV 504

  Fly   442 IGG-WFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNV 505
            :|| |...|.|   ...:|:||||||.||.||||||||||||||||||||||||||||:||||||
Mosquito   505 MGGVWGEPDVS---QQHDEVPTKRGASPTLIEWLILAWVSGLIWSEVKQLWDVGLQEYVNDMWNV 566

  Fly   506 IDFVTNSLYVATVALRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKL 570
            |||||||||||||||||||:|:|||||.||..|.|||||:||.||||||||||||||||||||||
Mosquito   567 IDFVTNSLYVATVALRVVSYFEVQKEMTYNKFAADLPREKWDTWDPMLISEGLFSAANIFSSLKL 631

  Fly   571 VYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSA 635
            ||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||:||..|.
Mosquito   632 VYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFSSGLNQLLWYYADLEKKRCPDVSSFSG 696

  Fly   636 LLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVI 700
             ||:..| |||||||||||:|||||.||||||||||:||::||||||||||||||||||||||||
Mosquito   697 -LNITAT-DPNACIVWRRFANLFETIQTLFWAVFGLVDLENFELDGIKIFTRFWGMLMFGTYSVI 759

  Fly   701 NIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKW 765
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||::|..:|
Mosquito   760 NIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSLFYIFQW 824

  Fly   766 MRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNE 830
            ::|.||..|.|.::||:||||||.:|||:|||:||.|||||||||||||||||||||||||||||
Mosquito   825 VKRKFCGHSKAVKKEHMKTIRRKVKQASERDFRYQSIMRNLVRRYVTVEQRKAESQGVTEDDVNE 889

  Fly   831 IKQDISAFRCELVEILKNSGMDTNVTAGQGGG-GGKKNRQKERRLMKGFNIAPPGSTGS---LAP 891
            |||||||||||||||||||||:|.:..|||.| |||||||||||||||||||||.:..:   |.|
Mosquito   890 IKQDISAFRCELVEILKNSGMNTAIATGQGSGVGGKKNRQKERRLMKGFNIAPPPAPDAGQHLTP 954

  Fly   892 VAEFSTSLDNYDNQHEILSSTLSTLFTP-------NFMHKRQQSQAGSGGGGSESP---TTPTAP 946
            |:||...|.:: :.||:.:.......||       |.|| :..||:.|..|.:.:|   ....||
Mosquito   955 VSEFIAQLPDH-SPHELFAGVFGPGLTPKKALHQVNPMH-QYSSQSQSSFGENNNPIHRLAKLAP 1017

  Fly   947 QGTQGAAMTASSQVTKYNKSALKPYNKRIAGHKKRWGTLIEAAKVGNVSKMLGRSKSEDSVCN-- 1009
                           |:|..:      |...|||||||||||||.|:|||.:|||:|||||||
Mosquito  1018 ---------------KFNSKS------RPGSHKKRWGTLIEAAKHGSVSKFIGRSRSEDSVCNHG 1061

  Fly  1010 ------SSHTSTPV-------------------------------------HGQMRVTYAQNSPQ 1031
                  :||:::|.                                     |.:.|........:
Mosquito  1062 PGRGESASHSNSPASDEAITESPSDSNPSLDRPDVEQCPDPHKHHNQHHKHHNRSRTDRGHQDRR 1126

  Fly  1032 QEYGYHGETSSTTISTPTPTISVVSNSPAAHAG-VGSHFFHTTSGLTAIAALKRKRKKFSSSKNI 1095
            |    ||.:..|...:.:.|  ..:|......| ..:|.:|...|  |:|||||||||||:|:|.
Mosquito  1127 Q----HGGSDRTQQHSSSGT--ATANGKNGRDGKEHAHHYHLHFG--ALAALKRKRKKFSNSRNS 1183

  Fly  1096 CPVTE------SVA-AANAAEILNDKTLKRVSSYPAAEAGVQHNPAQLVKPRRHEQTQSQHDSVE 1153
            .||.|      ||. |.......:.|.|||.||.|...|..:......|:|.|||.||||..|:|
Mosquito  1184 SPVLEPPCELPSVTNAITTTGNTSSKVLKRASSVPTRGASDEPEATGSVRPARHEATQSQQHSIE 1248

  Fly  1154 TNSTFTLSIDPSNT 1167
            ........:.||.|
Mosquito  1249 QQLEGAAPLTPSTT 1262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trpgamma	NP_001137830.2	trp	77..841	CDD:273311	650/764 (85%)
		ANK repeat	118..147	CDD:293786	25/28 (89%)
		ANK repeat	175..217	CDD:293786	33/41 (80%)
		TRP_CaM_bind1	865..>891	CDD:467881	20/28 (71%)
Trpgamma	XP_061512371.1	None